Results 101 to 110 of about 9,269,203 (381)
Development of the Innate Immune Response in NestlingTree Swallows (Tachycineta bicolor) [PDF]
, 2009 The innate immune system provides an immediate, short term, first line of defense from pathogens; its appearance early in development in vertebrates is evidence of its critical importance.
Stambaugh, T.R.
core +1 more source
Novel Defense Mechanisms in the Armor of the Scales of the “Living Fossil” Coelacanth Fish
Advanced Functional Materials, 2018 Here, experiments and analysis revealing the unique defense mechanisms of the coelacanth, a lobe‐finned fish termed a “living fossil”, are reported, as it was considered to be extinct until 1938, but extant for 400 million years. This defense is provided
Haocheng Quan +4 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Patient Preference and Adherence, 2010 Thomas Hyphantis1, Spiros Katsoudas2, Sonia Voudiclari31Associate Professor of Psychiatry, Department of Psychiatry, Medical School, University of Ioannina, Ioannina, Greece; 2Nephrologist, Renal Clinic, Hippocration General Hospital, Athens, Greece ...
Thomas Hyphantis +2 more
doaj
Defense Mechanisms of Plants to Insect Pests: From Morphological to Biochemical Approach
Trends in Technical & Scientific Research, 2018 Plant defense against insect herbivores is just one of multiple layers of interactions. In addition, plants are being utilized as nutrition source and shelter by parasitizing fungi, bacteria and viruses, along with vertebrates such as birds, lizards and ...
Tibebu Belete
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Defense Mechanisms against Viral Infection in Drosophila: RNAi and Non-RNAi
Viruses, 2018 RNAi is considered a major antiviral defense mechanism in insects, but its relative importance as compared to other antiviral pathways has not been evaluated comprehensively.
L. Swevers, Jisheng Liu, G. Smagghe
semanticscholar +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Defense Mechanisms in Substance Abusers’ Families
Research on Addiction, 2016 Objective: The aim of this study was to investigate the defensive mechanisms and styles in substance users and abusers’ families. Method: A descriptive research design was used for the purpose of the study. The sample consisted of 280 participants (
H Jana Abadi, N Zamani
doaj
A novel Arabidopsis pathosystem reveals cooperation of multiple hormonal response-pathways in host resistance against the global crop destroyer Macrophomina phaseolina. [PDF]
, 2019 Dubbed as a "global destroyer of crops", the soil-borne fungus Macrophomina phaseolina (Mp) infects more than 500 plant species including many economically important cash crops. Host defenses against infection by this pathogen are poorly understood.
Alsalek, Natalie +6 more
core +1 more source