Results 81 to 90 of about 1,154,898 (248)

Ego mechanisms of defense are associated with patients’ preference of treatment modality independent of psychological distress in end-stage renal disease

open access: yesPatient Preference and Adherence, 2010
Thomas Hyphantis1, Spiros Katsoudas2, Sonia Voudiclari31Associate Professor of Psychiatry, Department of Psychiatry, Medical School, University of Ioannina, Ioannina, Greece; 2Nephrologist, Renal Clinic, Hippocration General Hospital, Athens, Greece ...
Thomas Hyphantis   +2 more
doaj  

Psychodynamic aspects of communication skills training: a pilot study [PDF]

open access: yes, 2018
Goals of work:: Communication between patients and oncology clinicians is a key element of cancer care. Emotionally charged consultations may trigger clinicians' defense mechanisms, protecting them from painful emotions.
Bernard, Mathieu   +5 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Mediating Role of Defensive Mechanisms in the Relationship between Social Phobia and Alexithymia in University Students

open access: yesJournal of Holistic Nursing and Midwifery, 2020
Introduction: Psychological factors play a key role in peoplechr('39')s emotional responses to different social situations.  Objective: This study aimed to investigate the mediating role of defense mechanisms in the relationship between social phobia and
Mansour Nasiri   +2 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Defense Mechanisms in Substance Abusers’ Families

open access: yesResearch on Addiction, 2016
Objective: The aim of this study was to investigate the defensive mechanisms and styles in substance users and abusers’ families. Method: A descriptive research design was used for the purpose of the study. The sample consisted of 280 participants (
H Jana Abadi, N Zamani
doaj  

Emerging strategies to target metastasis and therapy resistance in melanoma

open access: yesMolecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

ME-Net: Towards Effective Adversarial Robustness with Matrix Estimation

open access: yes, 2019
Deep neural networks are vulnerable to adversarial attacks. The literature is rich with algorithms that can easily craft successful adversarial examples. In contrast, the performance of defense techniques still lags behind.
Katabi, Dina   +3 more
core  

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