Results 71 to 80 of about 1,154,898 (248)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Exploring clusters of defense styles, psychiatric symptoms and academic achievements among medical students: a cross-sectional study in Pakistan

open access: yesBMC Research Notes, 2018
Objective The clusters of participants with a homogeneous psychological make-up can be identified using sophisticated machine learning techniques such as the two-step clustering algorithm.
Ahmed Waqas   +4 more
doaj   +1 more source

The assessment of stress level, anxiety, depressive symptoms, and defense mechanisms among Polish and English medical students

open access: yesAnnals of General Psychiatry, 2020
Introduction Medical education is proven to be associated with a high degree of psychological stress. Different coping strategies used by students have been investigated on their efficacy. So far, studies on medical students have been limited to a single
M. Pawlaczyk   +3 more
doaj   +1 more source

Chitosanase may enhance anti-fungal defense responses in transgenic tobacco [PDF]

open access: yes, 2003
Chitosanase is an enzyme, similar to chitinase, capable of hydrolyzing the β-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially acetylated chitosan polymers found in fungal cell walls.
Hendrix, Bill L., Stewart, James McD.
core   +2 more sources

Comparative analysis of Salmonella susceptibility and tolerance to the biocide chlorhexidine identifies a complex cellular defense network [PDF]

open access: yes, 2014
peer-reviewedChlorhexidine is one of the most widely used biocides in health and agricultural settings as well as in the modern food industry. It is a cationic biocide of the biguanide class. Details of its mechanism of action are largely unknown.
Aine eSheridan   +13 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Defense mechanisms in psychological health and sport success of athletes [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2017
Introduction: Defense mechanisms represent a crucial component of our capacity to maintain emotional homeostasis. The present study is carried out with the purpose of determining the predictability of psychological health and sport success by defense ...
Afrooz Mousavi   +2 more
doaj  

Development of the Innate Immune Response in NestlingTree Swallows (Tachycineta bicolor) [PDF]

open access: yes, 2009
The innate immune system provides an immediate, short term, first line of defense from pathogens; its appearance early in development in vertebrates is evidence of its critical importance.
Stambaugh, T.R.
core   +1 more source

The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]

open access: yes, 2012
The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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