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Mössbauer spectroscopy of iron chelated by deferoxamine

Biochimica et Biophysica Acta (BBA) - General Subjects, 1972
Abstract Mossbauer spectra of Fe2+ and Fe3+ in the presence of deferoxamine, an ironchelating drug, were measured under several conditions of temperature and applied magnetic field. Well-resolved spectra of magnetically dilute Fe3+-deferoxamine samples were obtained at 4.2°K in a weak or zero field, which indicated a single, highspin species with ...
Jay L. Bock, George Lang
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The Effects of Deferoxamine Mesylate and Hypoxia on the Cochlea

Acta Oto-Laryngologica, 1987
Deferoxamine mesylate (DF) is a chelating agent used for the treatment of iron overload. Recently audiological testing of patients on long-term treatment with this drug indicated the possibility of an ototoxic side effect (1). We administered DF to chinchillas with both acute and chronic regimes.
Robert V. Harrison, Makoto Shirane
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Inhibition of peroxidase-catalyzed reactions by deferoxamine

Archives of Biochemistry and Biophysics, 1988
Phagocytes generate superoxide (O2-.) and hydrogen peroxide (H2O2) and their interaction in an iron-catalyzed reaction to form hydroxyl radicals (OH.) (Haber-Weiss reaction) has been proposed. Deferoxamine chelates iron in a catalytically inactive form, and thus inhibition by deferoxamine has been employed as evidence for the involvement of OH ...
Ann M. Waltersdorph   +1 more
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Assessment of the developmental toxicity of deferoxamine in mice

Archives of Toxicology, 1995
Deferoxamine (DFO), an efficient chelating agent available for the treatment of iron and aluminium overload, was evaluated for developmental toxicity in Swiss mice. Intraperitoneal injections of DFO were given to pregnant animals at 0, 44, 88, 176, and 352 mg/kg per day on gestational days 6 through 15.
Jacinto Corbella   +2 more
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Schießscheiben-Makula durch Deferoxamin-Behandlung

Klinische Monatsblätter für Augenheilkunde, 2004
A bull's-eye maculopathy can be provoked by drugs.A 67-year-old man observed transient green-yellow spots with both eyes. The visual acuity was 1.0 in the right eye and 0.9 in the left. Tiny pigmentary irregularities of the macula were observed by ophthalmoscopy. Fluorescein angiography revealed a cockade formation of the macula.
D. Schmidt, J. Finke
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The ototoxicity of deferoxamine mesylate

American Journal of Otolaryngology, 1995
Hidetaka Kanno   +2 more
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Deferoxamine Therapy in High-Ferritin Diabetes

Diabetes, 1989
Serum ferritin and diabetes control were evaluated in 18 White patients with poorly controlled type II (noninsulin-dependent) diabetes who had no known causes of iron-storage disorder. Serum ferritin levels were found to be elevated with normal serumiron and total iron-binding capacity in 9 of the 18 patients studied.
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Deferoxamin

2017
D. Meißner, T. Arndt
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Therapie der Hämosiderose mit Deferoxamin

DMW - Deutsche Medizinische Wochenschrift, 2008
Wolfgang Stremmel, Georg Strohmeyer
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