Results 41 to 50 of about 13,449 (262)
Background: Implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy (CRT) reduce sudden cardiac death and all-cause mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ahmed AlTurki +4 more
doaj +1 more source
T-Wave Oversensing with Contemporary Implantable Cardioverter–Defibrillators
Background: Implantable cardioverter–defibrillators (ICDs) need to reliably detect ventricular tachycardia (VT) and ventricular fibrillation (VF) while avoiding T-wave oversensing (TWOS), which is associated with a risk of inappropriate therapies.
Marc Strik +7 more
doaj +1 more source
External defibrillation on an implantable defibrillator [PDF]
To the Editor: Despite the best efforts of healthcare providers, guideline-conform treatment failure is expected to occur, particularly in real-world emergency situations [1]. In the case reported here, a 79-year-old man with a history of coronary artery disease and implantation of a cardioverter defibrillator (ICD) presented to the emergency room with
John Chiladakis +2 more
openaire +1 more source
Biointegrated Battery‐Based Electroceuticals
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou +6 more
wiley +1 more source
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo +27 more
wiley +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
ABSTRACT Background Deflectable delivery systems have been introduced to enhance coaxial alignment and procedural efficacy during left atrial appendage occlusion (LAAO), yet randomized comparisons with conventional fixed‐curve systems are lacking. Aims The GUIDE‐LAAO trial evaluated whether the TruSteer deflectable delivery system is non‐inferior to ...
Philippe Taieb +3 more
wiley +1 more source
Cardiac defibrillators are critical medical devices designed to restore normal heart rhythm during life-threatening arrhythmias, such as ventricular fibrillation and pulseless ventricular tachycardia.
Moein Mahmoodi
doaj +1 more source
ABSTRACT Background Hypertrophic cardiomyopathy is associated with alterations in coronary microvascular function which have variable pathophysiologic mechanisms, and variable reversibility acutely and chronically following alcohol septal ablation (ASA).
Vojko V. Misevic +12 more
wiley +1 more source
Indications of Implantable Defibrillator
Implantable cardioverter defibrillators are devices capable of detecting and terminating ventricular tachycardias or fibrillations. They are utilized in the treatment of severe ventricular tachyarrhythmias, and their efficacy in the prevention of sudden death is demonstrated.
openaire +2 more sources

