A Reassessment of Prophylactic Antibiotics in Low‐Infection‐Risk Electrophysiology Procedures
ABSTRACT Certain electrophysiology (EP) procedures are associated with minimal tissue disruption and do not involve permanent transvenous leads. As a result, these interventions carry a lower risk of device‐ or procedure‐related infection. These procedures include placement of implantable cardiac monitors, leadless pacemakers, and left atrial appendage
Rahel M. Sileshi +14 more
wiley +1 more source
Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps
Overview of the safety profile of pulsed field ablation (PFA), highlighting established safety advantages, procedure‐related complications, electroporation‐specific effects, and key areas of ongoing uncertainty, particularly for ventricular applications.
Dakota de Cecco +3 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li +19 more
wiley +1 more source
Response to the letter regarding 'Outcomes of functional ventricular tachycardia ablation vs. medical therapy in Chagas cardiomyopathy patients with implantable cardioverter-defibrillators: a competing risks analysis'. [PDF]
do Carmo AAL +2 more
europepmc +1 more source
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat +6 more
wiley +1 more source
The ECG as a Discovery Instrument for Sudden Cardiac Death. [PDF]
Nahrendorf M, Bapat A.
europepmc +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
Incidence of refibrillation and shock-resistant ventricular fibrillation during OHCA when treated with a public access defibrillator: implications for CPR timing in lay rescuer-treated OHCA. [PDF]
Kernaghan A +7 more
europepmc +1 more source

