Results 161 to 170 of about 1,617,861 (313)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Obesity and Its Association With Micronutrient Deficiency Among Mexican Children and Adolescents: A Systematic Review and Meta-analysis. [PDF]
Nutr RevHerrera-González A +3 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Glucose-6-phosphate-dehydrogenase deficiency as a risk factor in proliferative disorder development
, 2009 Glucose-6-phosphate dehydrogenase (G6PD) is an important site of metabolic control in the pentose phosphate pathway (PPP) which provides reducing power (NADPH) and pentose phosphates.
Claudia Abete +9 more
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A Study of Mineral Deficiency Symptoms of Carica Papaya, L.
, 2014 為說明木瓜營養狀況，本實驗利用水耕法，分期建立要素之個別缺乏症狀，並拍照紀錄。提供果農簡易分辨法，迅速測定養分供應情況，隨時改進肥培管理。結果如下: (一)缺氧:植株矮小。葉片黃化(下位葉首先發生)。 (二)缺磷:植株生長緩慢、矮小、葉片暗綠易脫落，根部色素有累積現象，呈深粉紅色。 (三)缺鉀:葉邊緣組織壞死，呈波狀，有向內捲之趨勢。 (四)缺鈣:新葉邊緣壞疸，頂芽生長受到抑制，根部有腐爛現象。 (五)缺鎂:葉脈間葉肉黃化，後期葉邊緣枯萎，病症首先出現在下位葉。 (六)缺鐵:初期幼葉邊緣黃化，
K. C. Lee +7 more
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