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Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha +55 more
core +6 more sources
Temporary nutrient deficiency - a difficult case for diagnosis and prognosis by plant analysis [PDF]
Plant analysis aims to either detect deficiency at the time of sampling (diagnosis) or predict its occurrence at a later stage of growth (prognosis). Its use is based on the presumption that the plant nutrient status will either be constant with plant ...
Bell, R.W.
core +2 more sources
GATA2 deficiency is a germline disease that causes a wide spectrum of phenotypes including viral and bacterial infections, cytopenias, myelodysplasia, myeloid leukemias, pulmonary alveolar proteinosis and lymphedema. The age of clinical presentation ranges from early childhood to late adulthood, with most occurring in adolescence to early adulthood. We
Amy P, Hsu +2 more
openaire +2 more sources
Introduction Rilpivirine (RPV) is a second‐generation non‐nucleoside reverse transcriptase inhibitor (NNRTI) that was recently approved for the treatment of antiretroviral‐naïve individuals with HIV‐1 viral load of
Miłosz Parczewski +4 more
doaj +1 more source
Clinical and molecular characterization of patients with adenylosuccinate lyase deficiency
Background Adenylosuccinate lyase deficiency (ADSLD) is an ultrarare neurometabolic recessive disorder caused by loss-of-function mutations in the ADSL gene. The disease is characterized by wide clinical variability.
Gerarda Mastrogiorgio +11 more
doaj +1 more source
What’s deficient in reward deficiency? [PDF]
It has been proposed that people with substance use disorders suffer from a reward deficiency syndrome. Sometimes this is framed as a pre-existing trait; sometimes it is framed as an acquired condition. Although the reward deficiency idea is often used as an explanation for excessive substance use, there is little consensus about the deficiency’s basis
openaire +2 more sources
Summary. Plasminogen deficiency has emerged as a well‐recognized disorder in which reduced levels of plasminogen lead to the development of pseudo membranes on mucosal surfaces, with subsequent end‐organ damage of the affected tissue. Ligneous conjunctivitis is the most recognizable, well‐documented, and common presentation of the clinical syndromes ...
R, Mehta, A D, Shapiro
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Vitamin D supplementation in systemic lupus erythematosus patients with vitamin D deficiency and insufficiency : the effect on disease activity, fatigue and interferon signature gene expression [PDF]
Background: Vitamin D deficiency is highly prevalent among patients with systemic lupus erythematosus (SLE) [1]. Evidence from multiple studies has shown that vitamin D deficiency in SLE is associated with a higher disease activity [2].
Borg, Andrew +4 more
core +1 more source
The HI content of the Eridanus group of galaxies [PDF]
The HI content of galaxies in the Eridanus group is studied using the GMRT observations and the HIPASS data. A significant HI deficiency up to a factor of 2-3 is observed in galaxies in the high galaxy density regions.
A. Biviano +31 more
core +3 more sources
Rare Mucocutaneous (Dermatological) Manifestations of Vitamin B12 Deficiency: A Case Series [PDF]
Vitamin B12 deficiency is widespread in developing countries, especially in Africa, India, South and Central America. It affects 1–2% of the general population and 10–15% of older adults and hospitalized patients.
Anuradha Deuri +4 more
doaj +1 more source

