Results 1 to 10 of about 1,004,607 (284)

Cobalt deficiency in cattle and its impact on production [PDF]

Pesquisa Veterinária Brasileira, 2021
: Two outbreaks of cobalt deficiency in beef cattle were diagnosed in Midwestern Brazil. We discuss the clinical, epidemiological, pathological features, therapeutic measures, and impact aspects of the production system associated with these outbreaks ...
Westerlly J. Silva, Carolina C. Guizelini, Gumercindo L. Franco, Rayane C.P. Veiga, Williane G. Arruda, Valter A. Nascimento, Elaine S.P. Melo, Ricardo A. A. Lemos   +7 more
doaj   +1 more source

Tocilizumab Use among Patients Who Developed Pulmonary Embolism in the Course of Cytokine Release Storm and COVID-19 Pneumonia—A Retrospective Study

Biomedicines, 2022
Introduction: Thromboembolic events, including mainly pulmonary embolisms and ischemic strokes, occur in up to one-third of COVID-19 patients. As efficacy of tocilizumab (TCZ) among patients with acute pulmonary embolism (PE) was not previously ...
Daniel Chober, Bogusz Aksak-Wąs, Jolanta Niścigorska-Olsen, Małgorzata Niekrasz, Miłosz Parczewski   +4 more
doaj   +1 more source

Phylodynamic Dispersal of SARS-CoV-2 Lineages Circulating across Polish–German Border Provinces

Viruses, 2022
Introduction: The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has evolved into a worldwide outbreak, with significant molecular evolution over time.
Karol Serwin, Bogusz Aksak-Wąs, Miłosz Parczewski   +2 more
doaj   +1 more source

Transmitted HIV drug resistance and subtype patterns among blood donors in Poland

Scientific Reports, 2021
Surveillance on the HIV molecular variability, risk of drug resistance transmission and evolution of novel viral variants among blood donors remains an understudied aspect of hemovigilance.
Miłosz Parczewski, Ewa Sulkowska, Anna Urbańska, Kaja Scheibe, Karol Serwin, Piotr Grabarczyk   +5 more
doaj   +1 more source

NHEJ Deficiency and Disease [PDF]

Molecular Cell, 2001
In mouse and human, diseases associated with deficiency of DNA ligase IV, a protein involved in DNA double-strand break repair, have been identified. Manifestation of some of these disease phenotypes, namely tumorigenesis, may require additional checkpoint deficiencies.
Maria Jasin, Andrew J. Pierce
openaire   +3 more sources

Antibody deficiency diseases [PDF]

European Journal of Immunology, 2008
AbstractPrimary immunodeficiency diseases are rare disorders characterized by quantitative or qualitative defects in cells or components in the immune system, resulting in a high degree of susceptibility to various types of infections. During differentiation, stem cells undergo a series of discrete steps, governed by a large number of different genes ...
Lennart Hammarström, Qiang Pan-Hammarström   +1 more
openaire   +3 more sources

Molecular epidemiology and HIV-1 variant evolution in Poland between 2015 and 2019

Scientific Reports, 2021
The occurrence of HIV-1 subtypes differs worldwide and within Europe, with non-B variants mainly found across different exposure groups. In this study, we investigated the distribution and temporal trends in HIV-1 subtype variability across Poland ...
Karol Serwin, Anna Urbańska, Kaja Scheibe, Magdalena Witak-Jędra, Maria Jankowska, Maria Hlebowicz, Monika Bociąga-Jasik, Anna Kalinowska-Nowak, Martyna Biała, Hubert Ciepłucha, Władysław Łojewski, Anita Olczak, Elżbieta Jabłonowska, Aldona Kowalczuk-Kot, Błażej Rozpłochowski, Adam Witor, Miłosz Parczewski   +16 more
doaj   +1 more source

COVID-19 vaccination in patients with primary immunodeficiencies: an international survey on patient vaccine hesitancy and self-reported adverse events

Frontiers in Immunology, 2023
IntroductionThe Sars-CoV-2 pandemic caused great concern for this novel virus among patients with primary immunodeficiency (PID) or inborn errors of immunity (IEI) and their families.
Martine Pergent, Filomeen Haerynck, Filomeen Haerynck, Levi Hoste, Levi Hoste, Ann Gardulf, Ann Gardulf, Ann Gardulf   +7 more
doaj   +1 more source

Clinical and molecular characterization of patients with adenylosuccinate lyase deficiency

Orphanet Journal of Rare Diseases, 2021
Background Adenylosuccinate lyase deficiency (ADSLD) is an ultrarare neurometabolic recessive disorder caused by loss-of-function mutations in the ADSL gene. The disease is characterized by wide clinical variability.
Gerarda Mastrogiorgio, Marina Macchiaiolo, Paola Sabrina Buonuomo, Emanuele Bellacchio, Matteo Bordi, Davide Vecchio, Kari Payne Brown, Natalie Karen Watson, Benedetta Contardi, Francesco Cecconi, Marco Tartaglia, Andrea Bartuli   +11 more
doaj   +1 more source

Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity

Cells, 2022
Current research proves that immune dysregulation is a common feature of coronavirus disease 2019 (COVID-19), and immune exhaustion is associated with increased disease mortality.
Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski   +8 more
doaj   +1 more source