Results 1 to 10 of about 10,393,002 (426)

Modeling CSF-1 receptor deficiency diseases - how close are we? [PDF]

open access: yesFEBS J, 2022
The role of colony‐stimulating factor‐1 receptor (CSF‐1R) in macrophage and organismal development has been extensively studied in mouse. Within the last decade, mutations in the CSF1R have been shown to cause rare diseases of both pediatric (Brain ...
Chitu V, Gökhan Ş, Stanley ER.
europepmc   +2 more sources

A British Medical Association Lecture ON DEFICIENCY DISEASES, WITH SPECIAL REFERENCE TO RICKETS [PDF]

open access: greenBritish medical journal, 1924
our viOws on nutrition, so that emphasis on the importance of quality of foodstuffs, which developed as the result of the discovery of vitamins, has nlow in turn beeni supplemented by equal emphasis of the importance of balance and interaction of ...
E. Mellanby
openalex   +2 more sources

Antibody deficiency diseases [PDF]

open access: yesEuropean Journal of Immunology, 2008
AbstractPrimary immunodeficiency diseases are rare disorders characterized by quantitative or qualitative defects in cells or components in the immune system, resulting in a high degree of susceptibility to various types of infections. During differentiation, stem cells undergo a series of discrete steps, governed by a large number of different genes ...
Lennart Hammarström   +1 more
openaire   +4 more sources

Biological consequence of zinc deficiency in the pathomechanisms of selected diseases [PDF]

open access: yesJBIC Journal of Biological Inorganic Chemistry, 2014
From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current ...
Bernadeta Szewczyk   +3 more
core   +2 more sources

Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency

open access: yesNutrients, 2021
Magnesium plays an important role in many physiological functions. Habitually low intakes of magnesium and in general the deficiency of this micronutrient induce changes in biochemical pathways that can increase the risk of illness and, in particular ...
D. Fiorentini   +3 more
semanticscholar   +1 more source

Tocilizumab Use among Patients Who Developed Pulmonary Embolism in the Course of Cytokine Release Storm and COVID-19 Pneumonia—A Retrospective Study

open access: yesBiomedicines, 2022
Introduction: Thromboembolic events, including mainly pulmonary embolisms and ischemic strokes, occur in up to one-third of COVID-19 patients. As efficacy of tocilizumab (TCZ) among patients with acute pulmonary embolism (PE) was not previously ...
Daniel Chober   +4 more
doaj   +1 more source

Cobalt deficiency in cattle and its impact on production [PDF]

open access: yesPesquisa Veterinária Brasileira, 2021
: Two outbreaks of cobalt deficiency in beef cattle were diagnosed in Midwestern Brazil. We discuss the clinical, epidemiological, pathological features, therapeutic measures, and impact aspects of the production system associated with these outbreaks ...
Westerlly J. Silva   +7 more
doaj   +1 more source

Phylodynamic Dispersal of SARS-CoV-2 Lineages Circulating across Polish–German Border Provinces

open access: yesViruses, 2022
Introduction: The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has evolved into a worldwide outbreak, with significant molecular evolution over time.
Karol Serwin   +2 more
doaj   +1 more source

Transmitted HIV drug resistance and subtype patterns among blood donors in Poland

open access: yesScientific Reports, 2021
Surveillance on the HIV molecular variability, risk of drug resistance transmission and evolution of novel viral variants among blood donors remains an understudied aspect of hemovigilance.
Miłosz Parczewski   +5 more
doaj   +1 more source

NHEJ Deficiency and Disease [PDF]

open access: yesMolecular Cell, 2001
In mouse and human, diseases associated with deficiency of DNA ligase IV, a protein involved in DNA double-strand break repair, have been identified. Manifestation of some of these disease phenotypes, namely tumorigenesis, may require additional checkpoint deficiencies.
Maria Jasin, Andrew J. Pierce
openaire   +3 more sources

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