Results 51 to 60 of about 760,723 (266)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

EFFECT OF ATMOSPHERIC TEMPERATURE ON BLOOD CHANGES OF TOTAL OXIDATIVE STRESS INDEX, (OSI) AND LIPID PROFILE IN PERIPARTUM EWES [PDF]

Assiut Veterinary Medical Journal, 2019
Oxidative stress index (OSI) is recently used as a valid tool for providing an in depth picture about redox status and oxidative stress. The study was conducted on Fourteen multiparous, singleton bearing Osimi ewes (1.5-2 years, 35-40 kg) belonging to ...
HAYAM M. A. MONZALY, GHADA MOHAMED
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Hospital admissions for vitamin D related conditions and subsequent immune-mediated disease: record-linkage studies.

, 2013
BACKGROUND: Previous studies have suggested that there may be an association between vitamin D deficiency and the risk of developing immune-mediated diseases.
Giulio Disanto, Michael J Goldacre, Goldacre, R, Sreeram V Ramagopalan, Gavin Giovannoni, Raph Goldacre, Ramagopalan, SV, Goldacre, MJ, Goldacre, Michael, Giovannoni, G, Disanto, G   +10 more
core   +1 more source

Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Although iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, focusing on where inadequate
Adegboye, Oyelola A., Lee, Sooji, Addo, Isaac Yeboah, Abate, Semagn Mekonnen, Abate, Yohannes Habtegiorgis, Abie, Alemwork, Abukhadijah, Hana J., Adzigbli, Leticia Akua, Abouzid, Mohamed, Agyemang-Duah, Williams, Kim, Min Seo, Abualruz, Hasan, Ahmad, Aqeel, Abdullahi, Auwal, ElHafeez, Samar Abd, Abiodun, Olumide, Aburuz, Salahdein, Abebe, Mesfin, Ahmed, Syed Anees, Abdulkader, Rizwan Suliankatchi, Adnani, Qorinah Estiningtyas Sakilah, Son, Yejun, Fischer, Florian, Abedi, Armita, Adamu, Lawan Hassan, Abu-Zaid, Ahmed, Akinosoglou, Karolina, Agampodi, Suneth Buddhika, Abd-Elsalam, Sherief, Ahmad, Muayyad M., Abreu, Lucas Guimarães, Yon, Dong Keon, Aboagye, Richard Gyan, Shin, Jae Il, Ahmed, Ali, Akter, Ema, Abolhassani, Hassan, Hwang, Jiyoung, Abdoun, Meriem, Adane, Mesafint Molla, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Mehrunnisha Sharif, Ajami, Marjan, Adetunji, Charles Oluwaseun, Adekanmbi, Victor, Afzal, Saira, Ahmed, Haroon, Adeyeoluwa, Temitayo Esther, Ahmed, Ayman   +49 more
core   +2 more sources

ASSESSMENT OF ADENOSINE DEAMINASE (ADA) LEVEL IN PREGNANT EWES IN RELATION TO LIVER FUNCTION TEST AND SOME OXIDANT INDICATOR [PDF]

Assiut Veterinary Medical Journal, 2017
Pregnancy represents a major challenge to animal based on the analysis of immunological and metabolic responses. Thus, the aim of this study to assess the potential changes in adenosine deaminase (ADA) enzyme activity level, representative indicators of ...
GHADA MOHAMED, NASSER ABOU-KHALI
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease [PDF]

, 2011
Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort.
Brand, Stephan, Burkhard Göke, Breiteneicher, Simone, Göke, Burkhard, Ochsenkühn, Thomas, Fabian Schnitzler, Stephan Brand, Maria Weidinger, Thomas Ochsenkühn, Simone Breiteneicher, Beigel, Florian, Weidinger, Maria, Schnitzler, Fabian, Löhr, Beate, Seiderer, Julia, Laubender, Rüdiger P., Beate Löhr, Tillack, Cornelia, Cornelia Tillack, Florian Beigel, Julia Seiderer, Rüdiger P. Laubender   +21 more
core   +1 more source