Results 51 to 60 of about 1,194,112 (311)

Late-onset thymidine kinase 2 deficiency: a review of 18 cases [PDF]

, 2019
BACKGROUND: TK2 gene encodes for mitochondrial thymidine kinase, which phosphorylates the pyrimidine nucleosides thymidine and deoxycytidine. Recessive mutations in the TK2 gene are responsible for the 'myopathic form' of the mitochondrial depletion ...
Caballero Eraso, Candelaria, Domínguez González, Cristina, Fernández Torrón, Roberto, Fuiza Luces, Carmen, García García, Jorge M., Hernández Laín, Aurelio, Hernández Voth, Ana R., Paradas, Carmen, Rivas, Eloy, Sayas Catalán, Javier   +9 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

INDUCTION OF TOLERANCE BY ORAL ADMINISTRATION OF FACTOR VIII AND TREATMENT OF HEMOPHILA [PDF]

, 2011
Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a Subject a therapeutically effective amount of the deficient anti gen, wherein the antigen is not present in a liposome.
Alpan, Oral, Kamala, Tirumalai, Matzinger, Polly, Velander, William Hugold   +3 more
core   +1 more source

Iron metabolism of in­testinal mucosa in various blood diseases [PDF]

, 1964
For the investigation of iron metabolism in the intestinal mucosa in various　blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls　and 35 cases with various blood diseases.
Kimura, Ikuro, Kodani, Hidenari, Tsuchida, Junichiro   +2 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Visual and brainstem auditory evoked potentials in HCV-infected patients before and after interferon-free therapy — A pilot study

International Journal of Infectious Diseases, 2019
Introduction: The aim of this study was to investigate brain bioelectrical activity disturbances in HCV-positive patients before and 24 weeks after interferon-free therapy (DAA), using visual (VEP) and brainstem (BAEP) evoked potentials and advanced ...
Marta Waliszewska-Prosół, Joanna Bladowska, Maria Ejma, Katarzyna Fleischer-Stępniewska, Weronika Rymer, Marek Sąsiadek, Tomasz Pawłowski, Krzysztof Małyszczak, Małgorzata Inglot, Agnieszka Żelwetro, Przemysław Podgórski, Brygida Knysz   +11 more
doaj   +1 more source

Determinants and Clinical Significance of Musculoskeletal Symptoms in Patients With Chronic Graft-Versus-Host Disease

HemaSphere, 2022
Musculoskeletal symptoms in chronic graft-versus-host disease (cGVHD) are rare manifestations contributing to disease burden. This study assesses the frequency of muscle cramps, joint and muscle aches, and muscle weakness in a cohort of patients severely
Ana Zelic Kerep, Filip Pirsl, Seth Steinberg, Sandra Mitchell, Lauren Curtis, Noa Holtzman, Sencer Goklemez, Ervina Bilic, Edward Cowen, Dominique Pichard, Galen Joe, Leora Comis, Annie Im, Ann Berger, Laura Parsons-Wandell, Drazen Pulanic, Kristin Baird, Ronald Gress, Steven Pavletic   +18 more
doaj   +1 more source

Modeling TB-HIV syndemic and treatment [PDF]

, 2014
Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly human syndemic. In this article, we formulate a model for TB and HIV transmission dynamics.
Silva, Cristiana J., Torres, Delfim F. M.   +1 more
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

A study on the effect of rutin in the antibiotics enhancement controlling e. coli infection in broiler chicken [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
This study aimed to identify synergistic antibacterial combinations containing rutin in both in vivo and in vitro settings. Escherichia coli, a major cause of poultry mortality, was isolated from broiler chickens and tested for antibiotic resistance ...
Randa M. KHALLAF, Sahar S. ABD EL-HAMIED, Azza Z. REFAIE, Omnia A. ELEWASY, Safaa M. ELMESALAMY   +4 more
doaj   +1 more source