Results 71 to 80 of about 754,294 (266)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
BMC Oral HealthBackground This in vitro study aimed to evaluate the digital impression accuracy of a novel scannable healing abutment (s-HA) compared to a conventional scan body (CSB) using three intraoral scanners (IOSs) on a single implant.
Xing Chen +5 more
doaj +1 more source
TH17 deficiency in human disease [PDF]
Journal of Allergy and Clinical Immunology, 2012 The differentiation of naive T cells into distinct subsets of effector T cells is critical for effective immunity against a wide variety of infectious agents in the environment. Activation of innate immune responses by Candida species through pattern-recognition receptors directs the subsequent development of naive T cells into T(H)17 cells, which are ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
EFORT Open ReviewsBone defects cause life-threatening risks and reduced quality of life. Researchers are advancing electrical stimulation technologies through sustained innovation to address these challenges.
Xiuqing Wang +3 more
doaj +1 more source
[Prevention of iodine deficiency diseases: focus on regional targeted programs]. [PDF]
Probl Endokrinol (Mosk), 2022 Dedov II +6 more
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Experimental ochratoxicosis A in Nile tilapia and its amelioration by some feed additives
International Journal of Veterinary Science and Medicine, 2018 Ochratoxin A (OTA) formation prevention is not usually available so counteracting strategies are urgent. This study investigated the toxic effects of OTA on Nile tilapia with trials to neutralize these effects by using some feed additives.
Amany M. Diab +4 more
doaj +1 more source
Modeling CSF-1 receptor deficiency diseases - how close are we? [PDF]
FEBS J, 2022 Chitu V, Gökhan Ş, Stanley ER.
europepmc +1 more source