Results 1 to 10 of about 355 (256)

New characterization of congenital immunodeficiencies due to different functional alterations

, 2010
In the last thirty years of the 20th century, a formidable numbers of scientific discoveries in the field of PIDs were made. Many scientific papers have been published on the molecular and cellular basis of the immune response and on the mechanisms ...
Fusco, Anna
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Mammalian N-Glycan Branching Protects against Innate Immune Self-Recognition and Inflammation in Autoimmune Disease Pathogenesis [PDF]

, 2007
SummaryAutoimmune diseases are prevalent and often life-threatening syndromes, yet the pathogenic triggers and mechanisms involved remain mostly unresolved.
Tenno, Mari, Marth, Jamey D, Stone, Erica L., Farquhar, Marilyn G, Farquhar, Marilyn G., Green, Ryan S, Marth, Jamey D., Green, Ryan S., Lehtonen, Eero, Stone, Erica L   +9 more
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Immunodeficiency and Autoimmune Enterocolopathy Linked to NFAT5 Haploinsufficiency [PDF]

, 2015
The link between autoimmune diseases and primary immunodeficiency syndromes has been increasingly appreciated. Immunologic evaluation of a young man with autoimmune enterocolopathy and unexplained infections revealed evidence of immunodeficiency ...
Murray, Joseph A, Boland, Brigid S, Sandborn, William J, López-Rodríguez, Cristina, Zhang, Bing, Jepsen, Kristen, Aramburu, Jose, Banno, Asoka, Kim, Stephanie H, Chang, John T, Crowe, Sheila E, Harismendy, Olivier, Widjaja, Christella E, Su, H Irene, Stoven, Samantha, Ho, Samuel B, Bui, Jack D, Jones, Marilyn C, Marietta, Eric V, Khosroheidari, Mahdieh, Okugawa, Yoshinaga, Peterson, Michael R, Goel, Ajay   +22 more
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When obesity is desirable: a longitudinal study of the Miami HIV-1-infected drug abusers (MIDAS) cohort.

, 2000
Despite widespread nutrient deficiencies, a substantial proportion of the MIDAS cohort exhibits obesity, which has been linked to immune dysregulation in other clinical settings. Herein, the effects of obesity on immune function, disease progression, and
Campa, Adriana, Persaud, Navindra, Page, J B, Shor-Posner, G, Zhang, Guoyan, Baum, M K, J. Bryan Page, Persaud, N, Mary Ann Fletcher, Baum, Marianna, Miguez-Burbano, Maria-Jose, Quesada, J, Marianna K. Baum, Quesada, Jose, Page, J, Maria-Jose Miguez-Burbano, Adriana Campa, Jose Quesada, Fletcher, Mary, Guoyan Zhang, Navindra Persaud, Campa, A, Zhang, G, Miguez-Burbano, M J, Shor-Posner, Gail, Fletcher, Mary A, Gail Shor-Posner   +26 more
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Entering HIV Medical Care with AIDS in the Era of Immediate Access to Antiretroviral Treatment

Despite advancements in rapid HIV care access, a significant portion of people living with HIV (PLWH) still enter care with advanced disease (AIDS). Test and Treat/ Rapid Access (TTRA) programs focused on rapid detection and treatment are widespread in ...
Geffrard, Anjalie, Rodriguez, Allan E, Alvarez, Victoria, Botero, Valeria, Saltzman, Russell G, Kolber, Michael A   +5 more
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Pattern and Predictors of Weight Gain During Pregnancy Among HIV-1-Infected Women from Tanzania [PDF]

, 2003
Progression of HIV disease is often accompanied by weight loss and wasting. Gestational weight gain is a strong determinant of maternal and neonatal outcomes; however, the pattern and predictors of weight gain during pregnancy among HIV-positive women ...
Msamanga, Gernard, Antelman, Gretchen, Fawzi W., Wafaie, Villamor, Eduardo, Peterson E., Karen, Spiegelman, Donna   +5 more
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Tenofovir Disoproxil Fumarate, Emtricitabine, and Efavirenz Versus Fixed-Dose Zidovudine/Lamivudine and Efavirenz in Antiretroviral-Naive Patients: Virologic, Immunologic, and Morphologic Changes-A 96-Week Analysis

, 2006
BACKGROUND:In antiretroviral-naive patients, tenofovir disoproxil fumarate (TDF), emtricitabine (FTC), and efavirenz (EFV) demonstrated superior outcomes compared with fixed-dose zidovudine (ZDV)/lamivudine (3TC) and EFV through 48 weeks. Results through
Cheng, Andrew, McColl, Damian, DeJesus, Edwin, Chen, Shan-Shan, Toole, John, Campo, Rafael, Arribas, Jose, Pozniak, Anton, Gallant, Joel, Gazzard, Brian, Enejosa, Jeffrey   +10 more
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Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjects

, 2009
OBJECTIVES: To evaluate the association between baseline (BL) replication capacity (RC) (RCBL) and immunologic/virologic parameters (at BL and after 48 weeks on therapy) in HIV-1-infected subjects initiating antiretroviral therapy.
Magnani G, Sbreglia C, Monogram Biosciences, Ghinelli F, Robbins GK, Pollard RB, Galluzzo CM, Ambu S, Maserati R, Sollima S, Coronado O, Riva A, Gargiulo M, Delia S, Rinaldi E, Niero F, Alberici F, NIH/NIAID ACTG 384 Protocol Team, Macor A, Pasetti G, Marzi M, Abrescia N, Sacchini D, Spritzler JG, Bates M, Forcina G, Bassetti D, CASTELLI, Francesco, Vella S, Busto A, Chiesi C, Chiodo F, Guaraldi G, Asmuth DM, Soranzo ML, Borderi M, Johnson VA, Lie Y, Sterrantino G, Vichi Ospedale F, Izzo CM, Fasulo G, Zoboli G., Minoli L, Esposito R, Pia Germinario EA, Capetti A, CAROSI, Giampiero, Pirillo MF, Ferrari C, Weidler J, Arcieri R, Gandhi RT, Sighinolfi L, Chan ES, Amici R, Cargnel A, Di Biagio A, Nobile A, Di Pietro M, d'Ettorre G, d'Arminio Monforte A, Meraviglia P, Scalise G, Santoro D, Ciardi M, Polizzi C, Skowron G, Balotta C, Di Nallo R, Chirianni A   +70 more
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Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. [PDF]

, 2015
Peripheral nerve injury can trigger neuropathic pain in adults but not in infants; indeed, for unknown reasons, neuropathic pain is rare before adolescence. We show here that the absence of neuropathic pain response in infant male rats and mice following
Ji, RR, McKelvey, Rebecca, Ji, Ru Rong, Old, E, Fitzgerald, M, McKelvey, R, Berta, Temugin, Old, Elizabeth, Berta, T, Fitzgerald, Maria   +9 more
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Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.

, 2008
TNFRSF13B encodes transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), a B cell- specific tumor necrosis factor (TNF) receptor superfamily member.
McLean-Tooke, A, Holm, AM, Lawrence, TC, Bergbreiter, A, Belohradsky, BH, Ochs, HD, Webster, AD, Lougaris, V, Salzer, U, Bacchelli, C, Schaeffer, AA, Ugrinovic, S, Salzer, US, Kumararatne, DS, Gertz, ME, Franco, JL, Spickett, GP, Thrasher, AJ, Webster, ADB, Peter, HH, Pan-Hammar-Strom, Q, Birmelin, J, Maclean-Tooke, A, Pan-Hammarström, Q, Chapel, H, Buckridge, S, Suez, D, Schulze, I, Jennings, S, Hagena, T, Schneider, P, Hammarstrom, L, Anover-Sombke, S, Chapel, Helen, Urschel, S, Plebani, A   +35 more
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