Results 41 to 50 of about 155,356 (377)

Disseminated Rhodococcus equi infection in a patient with Hodgkin’s lymphoma [PDF]

open access: yesVojnosanitetski Pregled, 2014
Introduction. Rhodococcus (R) equi is an opportunistic, uncommon human pathogen that causes mainly infection in immunocompromised hosts. The disease is usually presented as subacute pneumonia that is mostly cavitary and sometimes bacteremic ...
Mikić Dragan   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Proteomic investigation and biomarker identification of lung and spleen deficiency syndrome in HIV/AIDS immunological nonresponders [PDF]

open access: diamond, 2023
Yi-Ting Wang   +10 more
openalex   +3 more sources

Primary and Secondary Immunodeficiency Diseases in Oncohaematology: Warning Signs, Diagnosis, and Management

open access: yesFrontiers in Immunology, 2019
Background: Immunodeficiencies (ID), in particular primary immunodeficiencies (PID), are often associated with haematological manifestations, such as peripheral cytopenias or lymphoproliferative syndromes.
Silvia Sánchez-Ramón   +48 more
doaj   +1 more source

Development of cytomegalovirus (CMV) immune recovery uveitis is associated with Th17 cell depletion and poor systemic CMV-specific T cell responses. [PDF]

open access: yes, 2011
Backgroundthe immune reconstitution inflammatory syndromes (IRIS) are a spectrum of inflammatory conditions associated with opportunistic infections and occurring in approximately16% of human immunodeficiency type 1 (HIV-1)-infected patients given ...
Hartigan-O'Connor, Dennis J   +4 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Health-Related Quality of Life in Primary Immune Deficient Patients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2006
The primary immunodeficiency (PI) disorders are abnormalities in development and maturation of the immune system. Individuals with PI disease may experience frequent infections, which limit their abilities to exhibit physical and psychological well-being
"Habibeh Mozaffari   +8 more
doaj  

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Personalidad y estabilidad psíquica en un grupo de pacientes adultos con inmunodeficiencia celular Personality and psychic stability in a group of adult patients with cellular immunodeficiency

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2000
Se realizó un estudio de 16 pacientes adultos con el diagnóstico de inmunodeficiencia celular (IC), con el objetivo de evaluar sus características de personalidad, perfil psicopatológico y nivel de ansiedad.
Raúl Martínez Triana   +2 more
doaj  

Evaluation of hearing and cochlear function by audiometric testing in patients with hyperemesis gravidarum [PDF]

open access: yes, 2015
INTRODUCTION: The aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG).METHODS: Twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included.
Demirtas, Ömer   +5 more
core   +2 more sources

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