Results 61 to 70 of about 355 (256)

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Family Study of Pediatric Patients with Primary Antibody Deficiencies

Iranian Journal of Allergy, Asthma and Immunology, 2013
Common variable immunodeficiency (CVID) and selective IgA deficiency (SIGAD) are the most common primary antibody deficiencies. These two diseases may have coincidence in one family and SIGAD can progress to CVID which suggest common underlying genetic ...
Nima Rezaei, Hassan Abolhassani, Amir Kasraian, Payam Mohammadinejad, Bamdad Sadeghi, Asghar Aghamohammadi   +5 more
doaj  

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort

, 2018
Background: Globally, 49% of the estimated 1.8 million children living with HIV are accessing antiretroviral therapy (ART). There are limited data concerning long-term durability of first-line ART regimens and time to transition to second-line.
Shanshan Li, Samuel Ayaya, Andrew Edmonds, Constantin T. Yiannoutsos, Van Nguyen, L., Nguyen, Lam Van, Irene Marete, Mofenson, Lynne M., Marie-Thérèse Obama, Beverly S. Musick, Lynne M. Mofenson, Obama, Marie-Thérèse, Newman, J.E., Sohn, Annette H., Mofenson, L.M., François T. Eboua, Leroy, Valériane, Marete, I., Musick, B.S., Edmonds, A., Davies, M.-A., Marete, Irene, Ayaya, Samuel, Sawry, S., Mary-Ann Davies, Wools-Kaloustian, Kara, Obama, M.-T., Musick, Beverly S., Davies, Mary-Ann, Li, S., Yotebieng, Marcel, Sawry, Shobna, Shobna Sawry, Edmonds, Andrew, Wools-Kaloustian, K., Newman, Jamie E., Valériane Leroy, Jamie E. Newman, Eboua, F.T., Tanoh Eboua, François, Lam Van Nguyen, Annette H. Sohn, Kara Wools-Kaloustian, Yotebieng, M., Yiannoutsos, Constantin T., Yiannoutsos, C.T., Ayaya, S., Sohn, A.H., Leroy, V., Marcel Yotebieng, Li, Shanshan   +50 more
core   +1 more source

Evaluation of Humoral Immune Function in Patients with Chronic Idiopathic Thrombocytopenic Purpura

Iranian Journal of Allergy, Asthma and Immunology, 2013
Coincidence of autoimmune diseases such as immune thrombocytopenic purpura (ITP) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (PAD). But there is no original study on immunological
Mohammad Saeid Rahiminejad, Mehrdad Mirmohammad Sadeghi, Payam Mohammadinejad, Bamdad Sadeghi, Hassan Abolhassani, Mohammad Mehdi Dehghani Firoozabadi, Seyed Mohammad Fathi, Hamid Rezvani, Gholamreza Bahoush, Mohammad Ali Ehsani, Mohammad Faranoush, Azim Mehrvar, Babak Torabi Sagvand, Mojtaba Ghadiani, Nima Rezaei, Asghar Aghamohammadi   +15 more
doaj  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

Psychiatric Aspects of Primary Immunodeficiency Diseases: The Parental Study

Iranian Journal of Allergy, Asthma and Immunology, 2013
Primary immunodeficiency diseases (PID) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. This study was designed to find out the most important origins and aspects of stressor in parents
Hassan Abolhassani, Asghar Aghamohammadi, Sarvenaz Pourjabbar, Mohammad Salehi Sadaghiani, Sina Nikayin, Anahita Rabiee, Amir Imanzadeh, Javad Mahmmoodi Gharaei, Mohammad Arbabi, Nima Rezaei   +9 more
doaj  

MHC Class II Deficiency with Normal CD4+ T Cell Counts: A Case Report

Iranian Journal of Allergy, Asthma and Immunology, 2018
Major histocompatibility complex (MHC) class II deficiency is a rare primary immunodeficiency disorder (PID) with less than 200 cases worldwide. Here, we report an 8 month–old girl with MHC class II deficiency with a novel homozygous mutation in RFXANK ...
Farhad Abolnezhadian, Ali Saeedi-Boroujeni, Sara Iranparast   +2 more
doaj   +1 more source