Results 61 to 70 of about 733,986 (259)

Gastric cancer, inflammatory bowel disease and polyautoimmunity in a 17-year-old boy: CTLA-4 deficiency successfully treated with Abatacept

, 2021
Gut involvement is frequent in immunologic disorders, especially with inflammatory manifestations but also with cancer. In the last years, advances in functional and genetic testing have improved the diagnostic and therapeutic approach to immune ...
Chiriaco, Maria, Amodio, Donato, Paola Zangari, Zangari, Paola, Di Matteo, Gigliola, Caterina Cancrini, Bertocchini, Arianna, Licciardello, Maria, Cozza, Raffaele, Silvia Di Cesare, Dall'Oglio, Luigi, Giulia Angelino, Cristina Cifaldi, Rea, Francesca, Giorgiana Madalina Ursu, Arianna Bertocchini, Luigi Dall’Oglio, De Angelis, Paola, Angelino, Giulia, Claudio Romano, Donato Amodio, Erminia Francesca Romeo, Martina Rinelli, Ursu, Giorgiana Madalina, Rinelli, Martina, Accinni, Antonella, Finocchi, Andrea, Alessandro Crocoli, Raffaele Cozza, Paola De Angelis, Andrea Finocchi, Romeo, Erminia Francesca, Crocoli, Alessandro, Francalanci, Paola, Romano, Claudio, Alessandro Inserra, Gigliola Di Matteo, Maria Licciardello, Faraci, Simona, Francesca Rea, Cifaldi, Cristina, Di Cesare, Silvia, Simona Faraci, Inserra, Alessandro, Cancrini, Caterina, Paola Francalanci, Maria Chiriaco, Antonella Accinni   +47 more
core   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Psychiatric Aspects of Primary Immunodeficiency Diseases: The Parental Study

Iranian Journal of Allergy, Asthma and Immunology, 2013
Primary immunodeficiency diseases (PID) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. This study was designed to find out the most important origins and aspects of stressor in parents
Hassan Abolhassani, Asghar Aghamohammadi, Sarvenaz Pourjabbar, Mohammad Salehi Sadaghiani, Sina Nikayin, Anahita Rabiee, Amir Imanzadeh, Javad Mahmmoodi Gharaei, Mohammad Arbabi, Nima Rezaei   +9 more
doaj  

MHC Class II Deficiency with Normal CD4+ T Cell Counts: A Case Report

Iranian Journal of Allergy, Asthma and Immunology, 2018
Major histocompatibility complex (MHC) class II deficiency is a rare primary immunodeficiency disorder (PID) with less than 200 cases worldwide. Here, we report an 8 month–old girl with MHC class II deficiency with a novel homozygous mutation in RFXANK ...
Farhad Abolnezhadian, Ali Saeedi-Boroujeni, Sara Iranparast   +2 more
doaj   +1 more source

Serostatus‐Specific Prognostic Profiles and Phenotype‐Dependent Therapeutic Windows in Autoimmune Encephalitis: A Multicenter Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background While autoimmune encephalitis (AE) outcomes vary, serostatus‐specific prognostic determinants and institutional clustering effects remain poorly characterized. We aimed to delineate the distinct prognostic architecture of AE, identifying serostatus‐specific risk factors and potential therapeutic windows.
Xiaohong Tang, Jingxian Wang, Kaixin Zhu, Zhen Zhang, Liao Wu, Wei Wang, Chang Li, Qingyun Li, Hao Li, Jinghua Chen, Zhangxu Lian, Bin Liu, Tengfei Liu, Chunmei Wen, Nuan Wang, Sen Qun, Lishun Xiao, Qingwei Lai   +17 more
wiley   +1 more source

Overlap in Immunologic Pathways Between Asthma and Primary Immunodeficiency Disorders

Journal of Human Immunity
BackgroundAsthma is traditionally conceptualized as a T helper 2 (Th2)-mediated inflammatory airway disease. However, increasing evidence suggests that primary immune dysregulation may underlie or phenotypically mimic asthma in a subset of patients ...
Jooyoung Moon
doaj   +1 more source

The variability of the harlequin mouse phenotype resembles that of human mitochondrial-complex I-deficiency syndromes. [PDF]

, 2008
BACKGROUND: Despite the considerable progress made in understanding the molecular bases of mitochondrial diseases, no effective treatments have been developed to date. Faithful animal models would be extremely helpful for designing such treatments.
Paule Bénit, Emmanuel Philippe Dassa, Brière Jean-Jacques, Rustin Pierre, Jean-Jacques Brière, Sergio Goncalves, Pierre Rustin, Bénit Paule, Goncalves Sergio, Dassa Emmanuel Philippe   +9 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management

Respiratory Research, 2018
Background Pulmonary complications are common in primary immunodeficiency diseases (PID) and contribute to morbidity and mortality in these patients. However, their varied presentation and a general lack of awareness of PID in this setting make early ...
Pere Soler-Palacín, Javier de Gracia, Luis Ignacio González-Granado, Carlos Martín, Carlos Rodríguez-Gallego, Silvia Sánchez-Ramón, Lung ID-Signal Group   +6 more
doaj   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source