Results 81 to 90 of about 591,453 (305)

Primary antibody deficiency syndromes

, 2018
Primary antibody deficiency syndromes (PAD) are a group of primary immunodeficiencies (PID) characterized by reduced production of immunoglobulins and recurrent respiratory tract infections.
Larsen, Carsten Schade, Katzenstein, Terese L   +1 more
core   +1 more source

Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People

, 2016
Introduction: Transgender populations have been underrepresented in HIV epidemiologic studies and consequently in HIV prevention, care, and treatment programs.
Baral, Stefan, Reisner, Sari, Scheim, Ayden, Poteat, Tonia, Xavier, Jessica   +4 more
core   +1 more source

HIV Protective Efficacy and Correlates of Tenofovir Blood Concentrations in a Clinical Trial of PrEP for HIV Prevention [PDF]

, 2014
Background: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy for which adherence is a known determinant of efficacy. Blood concentrations of PrEP medications are one objective marker of adherence.
Ndase, Patrick, Celum, Connie, Mugo, Nelly, Haberer, Jessica, Brantley, Justin, Donnell, Deborah, Bumpus, Namandjé N., Bangsberg, David R., Hendrix, Craig, Baeten, Jared M., Mujugira, Andrew   +10 more
core   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Efficacy and Safety of Dolutegravir/Lamivudine in Antiretroviral Therapy-Naive People Living With HIV-1 and With High-Level Viremia

BACKGROUND: Dual regimen dolutegravir/lamivudine (DOL/3TC) showed potent efficacy and favorable safety in both antiretroviral therapy-naive and therapy-experienced patients, but data from real life about naive people with high-level viremia are still ...
Bon, Isabella, Rigamonti C, Viale, Pierluigi, Colangeli V, Giglia M, Viale P., Calza, Leonardo, Cretella, Silvia, Calza L, Cretella S, Colangeli, Vincenzo, Rigamonti, Claudio, Bon I, Giglia, Maddalena   +13 more
core   +1 more source

Eliminating Preventable HIV-Related Maternal Mortality in Sub-Saharan Africa: What Do We Need to Know? [PDF]

, 2015
Introduction: HIV makes a significant contribution to maternal mortality, and women living in sub-Saharan Africa are most affected. International commitments to eliminate preventable maternal mortality and reduce HIV-related deaths among pregnant and ...
Sebitloane, Hannah, Kaida, Angela, Danel, Isabella, Watts, D. Heather, Turan, Janet M., Lapidos-Salaiz, Ilana, Langer, Ana, Wegner, Mary, Moran, Allisyn C., Kourtis, Athena P., Cooper, Diane, Kendall, Tamil, Dilmitis, Sophie, Lathrop, Eva   +13 more
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

A novel case of chronic mucocutaneous candidiasis: Overlap between autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy syndrome and hyper IgE syndrome

Indian Journal of Paediatric Dermatology, 2018
Chronic mucocutaneous candidiasis (CMC) is a clinical entity where extensive fungal infection of skin, hair, nail, and mucosa with Candida sp. is seen. It has got association with several immunological and endocrinal dysfunctions.
Bauyelal Mahto, Payel Kundu, Aniruddha Ghosh, Sandipan Dhar   +3 more
doaj   +1 more source

Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial

, 2016
Background: HIV-1 eradication may require reactivation of latent virus along with stimulation of HIV-1-specific immune responses to clear infected cells.
McBrine, Nicole, Porichis, Filippos, Sbrolla, Amy, Barouch, Dan, Bhardwaj, Nina, Kwon, Douglas, Macklin, Eric, Flynn, Theresa, McLean, Anna P., Peter, Lauren, Gandhi, Rajesh, Kavanagh, Daniel G., Walker, Bruce, Shopis, Janet R., Kaufmann, Daniel E.   +14 more
core   +1 more source

Preventing Unintended Pregnancy and HIV Transmission: Effects of the HIV Treatment Cascade on Contraceptive Use and Choice in Rural KwaZulu-Natal [PDF]

, 2015
Background: For women living with HIV, contraception using condoms is recommended because it prevents not only unintended pregnancy but also acquisition of other sexually transmitted infections and onward transmission of HIV.
Raifman, Julia, Chetty, Terusha, Bärnighausen, Till, Pillay, Deenan, Matthews, Philippa, Herbst, Kobus, Tanser, Frank, Mutevedzi, Tinofa   +7 more
core   +1 more source