Results 101 to 110 of about 355 (256)

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

JAIDS Journal of Acquired Immune Deficiency Syndromes

, 2011
Texto completo: acesso restrito. p. 202-207Background: HIV, hepatitis C (HCV), and human T-cell lymphotropic virus I (HTLV-1) are associated with high global burdens of disease, notably in resource-poor locales.
Page, Kimberly, Alves, Carlos Roberto Brites, Marchand, Chloe Le, Bahia, Fabianna Márcia Maranhão, Novais, Vinicius, Evans, Jennifer, Martins Netto, Eduardo   +6 more
core  

Magnitude and Determinants of CD4 Recovery After HAART Resumption After 1 Cycle of Treatment Interruption

, 2009
OBJECTIVE:The extent of immune reconstitution following HAART resumption after 1 cycle of treatment interruption (TI) is not well known.METHODS:Multicenter retrospective analysis of patients who discontinued HAART with a CD4 > 500 cells/microL.
MUSSINI, Cristina, Erikson LE, COSSARIZZA, Andrea, Touloumi G, Bratt G, Esposito R., Castagna A, Sighinolfi L, Sabin C, Lazzarin A, Bakoyannis G, Borghi V   +11 more
core   +1 more source

Inmunodeficiencia primaria combinada: Presentación de un caso Combined primary inmunodeficiency: a case report

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2001
Se reporta el caso de un niño de 6 años de edad con infecciones respiratorias y digestivas recurrentes desde los 8 meses de edad. El estudio inmunológico reveló marcada disminución de la activación linfocitaria, niveles disminuidos de subclases de IgG2 ...
Vianed Marsán Suárez, Rinaldo Villaescusa Blanco, Lázaro O del Valle Pérez, Ada A Arce Hernández, Isabel Torres Leyva, Consuelo Macías Abraham   +5 more
doaj  

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Case Report: Aplastic anemia related to a novel CTLA4 variant

Frontiers in Pediatrics
A 20-year-old male patient with a history of celiac disease came to medical attention after developing profound fatigue and pancytopenia. Evaluation demonstrated pan-hypogammaglobulinemia. There was no history of significant clinical infections.
Geoffrey Hall, Janet G. Markle, James Maiarana, Paul L. Martin, Jennifer A. Rothman, John W. Sleasman, Howard Lederman, Antoine E. Azar, Robert A. Brodsky, Talal Mousallem   +9 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Challenging Physiotherapy for Children with Ataxia Telangiectasia

Fysioterapeuten, 2008
The aim of this article is to provide insight in the challenges for physiotherapists in assessment and treatment of the rare, degenerative and grave neurological disease Ataxia Telangiectasia (AT).
Ellen Velema, Trudy Burgers
doaj