Results 151 to 160 of about 418,401 (247)

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia   +3 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran   +2 more
wiley   +1 more source

Effectiveness of Scientific Literacy and Communication E‐Modules in a Molecular Biology Course: A Qualitative and Quantitative Analysis

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT In previous work, we described the development and implementation of new pedagogical practices aimed at enhancing literacy, critical thinking, and communication skills development in a third‐year undergraduate molecular biology course. The online nature and large size of the course presented challenges regarding student engagement and access ...
Meghan Kates   +7 more
wiley   +1 more source

Optimization of Lithium‐Ion Battery Circular Economy in Electric Vehicles in Sustainable Supply Chain

open access: yesBattery Energy, Volume 4, Issue 2, March 2025.
Lithium batteries constitute a pivotal component in electric vehicles (EVs) owing to their rechargeability and high‐power output capabilities. ABSTRACT Lithium batteries constitute a pivotal component in electric vehicles (EVs) owing to their rechargeability and high‐power output capabilities.
Mohsen Alizadeh Afroozi   +4 more
wiley   +1 more source

Improving Diagnostic Accuracy for Surgical Pelvic Organ Prolapse: A Sequential Protocol Combining POP-Q Examination and Transperineal Ultrasound. [PDF]

open access: yesJ Clin Med
García-Mejido JA   +5 more
europepmc   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang   +5 more
wiley   +1 more source

Nested PCR as a superior diagnostic method for Acanthamoeba keratitis compared to conventional techniques. [PDF]

open access: yesSci Rep
Khaksar S   +13 more
europepmc   +1 more source

Hidden Markov graphical models with state‐dependent generalized hyperbolic distributions

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract In this article, we develop a novel hidden Markov graphical model to investigate time‐varying interconnectedness between different financial markets. To identify conditional correlation structures under varying market conditions and accommodate shape features embedded in financial time series, we rely upon the generalized hyperbolic family of ...
Beatrice Foroni   +2 more
wiley   +1 more source

Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis. [PDF]

open access: yesFront Cardiovasc Med
Mutarelli A   +11 more
europepmc   +1 more source

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