Results 81 to 90 of about 2,496,657 (311)
Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy
Advanced Science, EarlyView.This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge +14 more
wiley +1 more source
L’argumentation et les descriptions définies
Discours, 2019 Utterances in which a referentially used definite description occurs as subject term may sometimes receive an argumentative interpretation, according to which the subject serves to introduce and justify the predicate.
Kohei Kida
doaj +1 more source
Experimental Joint Estimation of Phase and Phase Diffusion Via Deterministic Bell Measurements
Advanced Science, EarlyView.This work employs Bell measurement, a form of entangling measurement, to estimate both the phase and its fluctuations in an optical interferometer. By incorporating a novel quantum effect at the measurement stage, the proposed method achieves the ultimate precision limit and demonstrates the significant potential of entangling measurements in multi ...
Ben Wang +4 more
wiley +1 more source
Advanced Science, EarlyView.Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma +15 more
wiley +1 more source
Advanced Science, EarlyView.Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang +10 more
wiley +1 more source
Filosofia Unisinos, 2016 One important aspect of the faculty of language, as understood in generative grammar, is its capacity to form operator-variable structures. Such structures are crucial for definite descriptions, as understood in the broadly Russellian tradition.
John Bolender
doaj +1 more source
A Corpus-Based Investigation of Definite Description Use
, 1997 We present the results of a study of definite descriptions use in written texts aimed at assessing the feasibility of annotating corpora with information about definite description interpretation.
Poesio, Massimo, Vieira, Renata
core +2 more sources
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Non-Declarative Sentences and the Theory of Definite Descriptions
Principia: An International Journal of Epistemology, 2004 This paper shows that Russell’s theory of descriptions gives the wrong se-mantics for definite descriptions occurring in questions and imperatives. Depending on how that theory is applied, it either assigns nonsense to per-fectly meaningful questions and
John-Michael Kuczynski
doaj
Antecedent selection techniques for high-recall roreference resolution [PDF]
, 2007 We investigate methods to improve the recall in coreference resolution by also trying to resolve those definite descriptions where no earlier mention of the referent shares the same lexical head (coreferent bridging). The problem, which is notably harder
Versley, Yannick
core