Results 61 to 70 of about 469,223 (286)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Natural and experimental definitive hosts of Fascioloides magna and Fasciola hepatica. [PDF]

, 2012
Fascioloides magna (giant liver fluke) and Fasciola hepatica (liver fluke) are veterinary and medically important endoparasites belonging to the class Trematoda, subclass Digenea. They are the causative agents of the diseases fascioloidosis (F.
Melounová, Klára
core   +1 more source

Angiostrongylus cantonensis Lungworms in Definitive and Intermediate Hosts, Madagascar, 2024

Emerging Infectious Diseases
We assessed the prevalence of the rat lungworm, Angiostrongylus cantonensis, in rats and snails in Toamasina, Madagascar, using molecular techniques.
Lanto A. Maminirina, Zaïna I. Bodoarison, Minoarisoa Rajerison, Séverine Ferdinand, Beza Ramasindrazana   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Effects of Cymatocarpus solearis (Trematoda: Brachycoeliidae) on its second intermediate host, the Caribbean spiny lobster Panulirus argus.

PLoS ONE, 2023
Many digenean trematodes require three hosts to complete their life cycle. For Cymatocarpus solearis (Brachycoeliidae), the first intermediate host is unknown; the Caribbean spiny lobster Panulirus argus is a second intermediate host, and the loggerhead ...
Tomás Franco-Bodek, Cecilia Barradas-Ortiz, Fernando Negrete-Soto, Rossanna Rodríguez-Canul, Enrique Lozano-Álvarez, Patricia Briones-Fourzán   +5 more
doaj   +1 more source

Echinococcus multilocularis coproantigen detection by enzyme-linked immunosorbent assay in fox, dog, and cat populations [PDF]

, 1999
A sandwich enzyme-linked immunosorbent assay (ELISA) for the detection of Echinococcus multilocularis coproantigens (EM-ELISA) was developed with polyclonal rabbit (solid phase) and chicken egg (catching) antibodies that were directed against E ...
Deplazes, P., Thompson, R.C.A., Alther, P., Eckert, J., Tanner, I.   +4 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Comprehensive Review of Alaria alata (Goeze 1782) (Platyhelminthes, Trematoda) in Different Animal Hosts

Pathogens
This review provides a comprehensive overview of the occurrence of Alaria alata (Goeze 1782) trematodes in first, second, definitive, and paratenic hosts, including wild and domestic animals.
Aneta Bełcik, Tomasz Cencek, Weronika Korpysa-Dzirba, Małgorzata Samorek-Pieróg, Jacek Karamon, Jacek Sroka, Jolanta Zdybel, Marta Skubida, Ewa Bilska-Zając   +8 more
doaj   +1 more source

Canine echinococcosis: genetic diversity of Echinococcus granulosus sensu stricto ( s.s. from definitive hosts [PDF]

, 2021
Canids, particularly dogs, constitute the major source of cystic echinococcosis ( CE infection to humans, with the majority of cases being caused by Echinococcus granulosus ( G1 genotype .
Griffiths, A., Lahmar, S., Buishi, I., Engliez, S.a., Craig, P.s., Elmestiri, F.m., Lett1, W., Torgerson, P.r., Reyes, M.m., Al-Hindi, A., Jenkins, D.j., Eljaki, A.a., Al-Hindi, Adnan, Alrefadi, M.a., Okamoto, M., Pointing, S., Boufana, B.   +16 more
core