Results 1 to 10 of about 4,226,477 (158)

WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three

Malaria Journal, 2020
Background The World Health Organization (WHO) recommends parasite-based diagnosis of malaria. In recent years, there has been surge in the use of various kinds of nucleic-acid amplification based tests (NAATs) for detection and identification of ...
Jane A. Cunningham, Rebecca M. Thomson, Sean C. Murphy, Maria de la Paz Ade, Xavier C. Ding, Sandra Incardona, Eric Legrand, Naomi W. Lucchi, Didier Menard, Samuel L. Nsobya, Agatha C. Saez, Peter L. Chiodini, Jaya Shrivastava   +12 more
doaj   +1 more source

Integrated analysis of humoral and T-cell responses to pneumococcal vaccination in allogeneic hematopoietic stem cell transplant recipients

Frontiers in Medicine
IntroductionAllogeneic hematopoietic stem cell transplant (HSCT) recipients remain highly susceptible to pneumococcal infection despite current vaccination strategies, and the contribution of T-cell–mediated immunity to protection in this population is ...
André Silva-Pinto, André Silva-Pinto, André Silva-Pinto, Ana Isabel Pinto, Ana Isabel Pinto, Pedro Curto, Joana Ribeiro, Joana Ribeiro, Ricardo Pinto, Ricardo Pinto, Juliana Bastos, Juliana Bastos, Lurdes Santos, Lurdes Santos, Joana Tavares, Joana Tavares, Anabela Cordeiro-da-Silva, Anabela Cordeiro-da-Silva   +17 more
doaj   +1 more source

Synthesis, Antiparasitic Activity and Substituent Effects of Methyl 5-(Hetero)aryl or Alicyclicaminothieno[2,3-b]pyridine-2-carboxylates

Molecules
Di(hetero) aryl and alicyclic amine derivatives of thieno[2,3-b]pyridine were synthesized in good to high yields (45–76%) via palladium-catalyzed Buchwald–Hartwig amination.
Francisco Ribeiro, Juliana P. Sousa, Nuno Santarém, Joana Tavares, Anabela Cordeiro-da-Silva, Maria-João R. P. Queiroz   +5 more
doaj   +1 more source

Colonization of Anopheles coustani, a neglected malaria vector in Madagascar

Parasite
Anopheles coustani has long been recognized as a secondary malaria vector in Africa. It has recently been involved in the transmission of both Plasmodium falciparum and P. vivax in Madagascar. As most secondary malaria vectors, An.
Andrianinarivomanana Tsarasoa M., Randrianaivo Fenomiaranjara T., Andriamiarimanana Mandaniaina R., Razafimamonjy Mihary R., Velonirina Haja J.S., Puchot Nicolas, Girod Romain, Bourgouin Catherine   +7 more
doaj   +1 more source

Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning

mBio, 2017
The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Jordan Wesolowski, Mary M. Weber, Agata Nawrotek, Cheryl A. Dooley, Mike Calderon, Claudette M. St. Croix, Ted Hackstadt, Jacqueline Cherfils, Fabienne Paumet   +8 more
doaj   +1 more source

A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection

Frontiers in Immunology, 2019
Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Norus Ahmed, Emanuel Heitlinger, Emanuel Heitlinger, Nicole Affinass, Anja A. Kühl, Natasa Xenophontos, Victor Hugo Jarquin, Victor Hugo Jarquin, Jenny Jost, Svenja Steinfelder, Svenja Steinfelder, Susanne Hartmann   +11 more
doaj   +1 more source

Plasmodium chabaudi AS Infection Induces CD4+ Th1 Cells and Foxp3+T-bet+ Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands

Frontiers in Immunology, 2019
Control and elimination of blood-stage Plasmodium chabaudi AS infection requires CD4+ Th1 cells that secrete IFN-γ and T follicular help (Tfh) cells together with B cell production of antibody.
Floriana Berretta, Floriana Berretta, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Mary M. Stevenson, Mary M. Stevenson   +6 more
doaj   +1 more source

IL-10-STAT3 axis preserves epithelial mitochondrial homeostasis during bacterial challenge

Gut Microbes
Increasing evidence implicates mitochondrial dysfunction in the pathogenesis of inflammatory bowel disease (IBD), with the IBD-associated pathobiont adherent-invasive E. coli-LF82 (AIEC) promoting epithelial mitochondrial depolarization and fragmentation
Saranya Navaneetha Krishnan, Amit Jaiswal, Armaan Mohan, Arthur Wang, Timothy E. Shutt, Derek M. McKay   +5 more
doaj   +1 more source

Synthesis of Tricyclic and Tetracyclic Lactone Derivatives of Thieno[2,3-b]pyrazine or Thieno[2,3-b]quinoline: Preliminary Antitumor and Antiparasitic Activity Evaluation

Molecules
Tricyclic and tetracyclic lactone derivatives of thieno[2,3-b]pyrazine or thieno[2,3-b]quinoline, and 2H-pyrones were prepared using different methodologies.
Maria F. Martins, Francisco Ribeiro, Ana Borges, Ricardo C. Calhelha, Nuno Santarém, Anabela Cordeiro-da-Silva, Maria-João R. P. Queiroz   +6 more
doaj   +1 more source

Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development. [PDF]

Front Vet Sci, 2023
Flores-Velázquez LM, Ruiz-Campillo MT, Herrera-Torres G, Martínez-Moreno Á, Martínez-Moreno FJ, Zafra R, Buffoni L, Rufino-Moya PJ, Molina-Hernández V, Pérez J.   +9 more
europepmc   +1 more source