Results 11 to 20 of about 62,021 (264)
Parasites & Vectors, 2017 Background Diagnosis of soil-transmitted helminths (STHs) has traditionally relied on stool microscopy, which has a number of critical deficiencies. Molecular diagnostics are powerful tools to identify closely related species, but the requirement for ...
Nour Rashwan +3 more
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HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis
Scientific Reports, 2018 Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to ...
Akil Hammami +3 more
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Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite
Molecular Systems Biology, 2020 Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant +8 more
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Open Research Europe, 2022 Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of ...
Jessica Bryant, Sebastian Baumgarten
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Diverse Requirements for Src-Family Tyrosine Kinases Distinguish Chlamydial Species
mBio, 2011 Chlamydiae are well known for their species specificity and tissue tropism, and yet the individual species and strains show remarkable genomic synteny and share an intracellular developmental cycle unique in the microbial world.
Jeffrey Mital, Ted Hackstadt
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International Journal for Parasitology: Drugs and Drug Resistance, 2020 (300 words): A lack of quantitative information on the species composition of parasite communities present in fecal samples is a major limiting factor for the sensitivity, accuracy and interpretation of the diagnostic tests commonly used to assess ...
Camila Queiroz +8 more
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Host–parasite interactions and the evolution of ploidy [PDF]
Proceedings of the National Academy of Sciences, 2004 Although the majority of animals and plants, including humans, are dominated by the diploid phase of their life cycle, extensive diversity in ploidy level exists among eukaryotes, with some groups being primarily haploid whereas others alternate between haploid and diploid phases.
Scott L, Nuismer, Sarah P, Otto
openaire +2 more sources
Multiple drug resistance in hookworms infecting greyhound dogs in the USA
International Journal for Parasitology: Drugs and Drug Resistance, 2021 Ancylostoma caninum is the most prevalent nematode parasite of dogs. We confirmed multiple-drug resistance (MDR) in several A. caninum isolates to all anthelmintic drug classes approved for the treatment of hookworms in dogs in the USA.
Pablo D. Jimenez Castro +9 more
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Disease Models & Mechanisms, 2020 Mature human erythrocytes contain a rich pool of microRNAs (miRNAs), which result from differentiation of the erythrocytes during the course of haematopoiesis.
Malabika Chakrabarti +4 more
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International Journal for Parasitology: Drugs and Drug Resistance, 2023 A large-scale Fecal Egg Count Reduction Test (FECRT) was integrated with ITS-2 rDNA nemabiome metabarcoding to investigate anthelmintic resistance in gastrointestinal nematode (GIN) parasites in western Canadian beef cattle.
Eranga L. De Seram +10 more
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