Results 11 to 20 of about 150,290 (299)

Trickle infection with Heligmosomoides polygyrus results in decreased worm burdens but increased intestinal inflammation and scarring

open access: yesFrontiers in Immunology, 2022
IntroductionIntestinal roundworms cause chronic debilitating disease in animals, including humans. Traditional experimental models of these types of infection use a large single-dose infection. However, in natural settings, hosts are exposed to parasites
Anupama Ariyaratne   +23 more
doaj   +1 more source

High levels of third-stage larvae (L3) overwinter survival for multiple cattle gastrointestinal nematode species on western Canadian pastures as revealed by ITS2 rDNA metabarcoding

open access: yesParasites & Vectors, 2020
Background The ability of infective larvae of cattle gastrointestinal nematode (GIN) species to overwinter on pastures in northerly climatic zones with very cold dry winters is poorly understood.
Tong Wang   +5 more
doaj   +1 more source

Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture

open access: yesmBio, 2022
The etiological agent of Rocky Mountain spotted fever, Rickettsia rickettsii, is an obligately intracellular pathogen that induces the polymerization of actin filaments to propel the bacterium through the cytoplasm and spread to new host cells.
Adam M. Nock   +2 more
doaj   +1 more source

Giardia spp. and the Gut Microbiota: Dangerous Liaisons

open access: yesFrontiers in Microbiology, 2021
Alteration of the intestinal microbiome by enteropathogens is commonly associated with gastrointestinal diseases and disorders and has far-reaching consequences for overall health.
Elena Fekete   +14 more
doaj   +1 more source

Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]

open access: yes, 2010
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ebert, D., Ganz, H.
core   +1 more source

Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model? [PDF]

open access: yes, 2010
Since its use as a model to study metazoan parasite culture and in vitro development, the plerocercoid of the tapeworm, Ligula intestinalis, has served as a useful scientific tool to study a range of biological factors, particularly within its fish ...
Carter, V, Dufour, S, Hoole, D
core   +1 more source

Influence of cold on host-parasite interactions. [PDF]

open access: yes, 1963
pt.
Arctic Aeromedical Laboratory (U.S.)   +2 more
core   +2 more sources

Isothermal diagnostic assays for the detection of soil-transmitted helminths based on the SmartAmp2 method

open access: yesParasites & Vectors, 2017
Background Diagnosis of soil-transmitted helminths (STHs) has traditionally relied on stool microscopy, which has a number of critical deficiencies. Molecular diagnostics are powerful tools to identify closely related species, but the requirement for ...
Nour Rashwan   +3 more
doaj   +1 more source

HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

open access: yesScientific Reports, 2018
Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to ...
Akil Hammami   +3 more
doaj   +1 more source

Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

open access: yesMolecular Systems Biology, 2020
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant   +8 more
doaj   +1 more source

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