Results 11 to 20 of about 532,266 (354)

Systems Analysis of Host-Parasite Interactions [PDF]

WIREs Systems Biology and Medicine, 2015
Parasitic diseases caused by protozoan pathogens lead to hundreds of thousands of deaths per year in addition to substantial suffering and socioeconomic decline for millions of people worldwide.
Justine Swann, N. Jamshidi, N. Lewis, E. Winzeler   +3 more
semanticscholar   +5 more sources

Host–parasite interactions: an intimate epigenetic relationship [PDF]

Cellular Microbiology, 2015
The epigenetics of host–pathogen interactions is emerging as an interesting angle from which to study how parasites have evolved sophisticated strategies to manipulate host gene transcription and protein expression.
K. Cheeseman, J. Weitzman
semanticscholar   +3 more sources

Chlamydia trachomatis suppresses host cell store-operated Ca2+ entry and inhibits NFAT/calcineurin signaling

Scientific Reports, 2022
The obligate intracellular bacterium, Chlamydia trachomatis, replicates within a parasitophorous vacuole termed an inclusion. During development, host proteins critical for regulating intracellular calcium (Ca2+) homeostasis interact with the inclusion ...
Nicholas B. Chamberlain, Zoe Dimond, Ted Hackstadt   +2 more
doaj   +1 more source

An Improved Method to Enrich Large Extracellular Vesicles Derived from Giardia intestinalis through Differential Centrifugation

Life, 2023
Giardia intestinalis is a flagellated unicellular protozoan that colonizes the small intestine, causing the diarrheal disease called giardiasis. The production of extracellular vesicles (EVs) by G. intestinalis and the role of these EVs in the parasite’s
Abel Sana, Izadora Volpato Rossi, Bruna Sabatke, Letícia Bassani Bonato, Lia Carolina Soares Medeiros, Marcel Ivan Ramirez   +5 more
doaj   +1 more source

Overview of Poultry Eimeria Life Cycle and Host-Parasite Interactions

Frontiers in Veterinary Science, 2020
Apicomplexan parasites of the genus Eimeria are organisms which invade the intestinal tract, causing coccidiosis, an enteric disease of major economic importance worldwide.
S. López-Osorio, J. Chaparro-Gutiérrez, L. Gómez-Osorio   +2 more
semanticscholar   +1 more source

Performance of a universal PCR assay to identify different Leishmania species causative of Old World cutaneous leishmaniasis

Parasites & Vectors, 2020
Background The characterization of Leishmania species is important for clinical management of the diseases and the epidemiological control of the parasite distribution.
Mahmoud Nateghi Rostami, Fatemeh Darzi, Mahin Farahmand, Mohsen Aghaei, Parviz Parvizi   +4 more
doaj   +1 more source

Trickle infection with Heligmosomoides polygyrus results in decreased worm burdens but increased intestinal inflammation and scarring

Frontiers in Immunology, 2022
IntroductionIntestinal roundworms cause chronic debilitating disease in animals, including humans. Traditional experimental models of these types of infection use a large single-dose infection. However, in natural settings, hosts are exposed to parasites
Anupama Ariyaratne, Anupama Ariyaratne, Sang Yong Kim, Stephen M. J. Pollo, Stephen M. J. Pollo, Shashini Perera, Shashini Perera, Hongrui Liu, Hongrui Liu, William N. T. Nguyen, Aralia Leon Coria, Aralia Leon Coria, Mayara de Cassia Luzzi, Mayara de Cassia Luzzi, Joel Bowron, Joel Bowron, Edina K. Szabo, Edina K. Szabo, Kamala D. Patel, James D. Wasmuth, James D. Wasmuth, Meera G. Nair, Constance A. M. Finney, Constance A. M. Finney   +23 more
doaj   +1 more source

High levels of third-stage larvae (L3) overwinter survival for multiple cattle gastrointestinal nematode species on western Canadian pastures as revealed by ITS2 rDNA metabarcoding

Parasites & Vectors, 2020
Background The ability of infective larvae of cattle gastrointestinal nematode (GIN) species to overwinter on pastures in northerly climatic zones with very cold dry winters is poorly understood.
Tong Wang, Russell W. Avramenko, Elizabeth M. Redman, Janneke Wit, John S. Gilleard, Douglas D. Colwell   +5 more
doaj   +1 more source

Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture

mBio, 2022
The etiological agent of Rocky Mountain spotted fever, Rickettsia rickettsii, is an obligately intracellular pathogen that induces the polymerization of actin filaments to propel the bacterium through the cytoplasm and spread to new host cells.
Adam M. Nock, Tina R. Clark, Ted Hackstadt   +2 more
doaj   +1 more source

Giardia spp. and the Gut Microbiota: Dangerous Liaisons

Frontiers in Microbiology, 2021
Alteration of the intestinal microbiome by enteropathogens is commonly associated with gastrointestinal diseases and disorders and has far-reaching consequences for overall health.
Elena Fekete, Elena Fekete, Elena Fekete, Thibault Allain, Thibault Allain, Thibault Allain, Affan Siddiq, Affan Siddiq, Affan Siddiq, Olivia Sosnowski, Olivia Sosnowski, Olivia Sosnowski, Andre G. Buret, Andre G. Buret, Andre G. Buret   +14 more
doaj   +1 more source