Results 41 to 50 of about 150,290 (299)
mBio, 2018 Strains of Rickettsia rickettsii, the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain ...
Stephanie S. Lehman +10 more
doaj +1 more source
mBio, 2021 Infection with the unicellular eukaryotic pathogen Plasmodium ...
Ameya Sinha +12 more
doaj +1 more source
Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq
International Journal for Parasitology: Drugs and Drug Resistance, 2016 The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal
Maeghan O'Neill +8 more
doaj +1 more source
Current Treatments to Control African Trypanosomiasis and One Health Perspective
Microorganisms, 2022 Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei.
Alberto Venturelli +9 more
doaj +1 more source
Evolution of spatially structured host–parasite interactions [PDF]
Journal of Evolutionary Biology, 2015 AbstractSpatial structure has dramatic effects on the demography and the evolution of species. A large variety of theoretical models have attempted to understand how local dispersal may shape the coevolution of interacting species such as host–parasite interactions.
Lion, Sébastien, Gandon, Sylvain
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
BMC Biology, 2021 Background Biomarker discovery remains a major challenge for predictive medicine, in particular, in the context of chronic diseases. This is true for the widespread protozoan Toxoplasma gondii which establishes long-lasting parasitism in metazoans ...
Céline Dard +9 more
doaj +1 more source
Frontiers in Immunology, 2022 Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by ...
Ana Rafaela Teixeira +26 more
doaj +1 more source
Avian malaria co-infections confound infectivity and vector competence assays of Plasmodium homopolare. [PDF]
, 2018 Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly. In the current study, we experimentally measured the vector competence of several Culex mosquitoes for a newly ...
Barker, Christopher M +5 more
core +1 more source
Host–parasite interactions: an intimate epigenetic relationship [PDF]
Cellular Microbiology, 2015 The epigenetics of host-pathogen interactions is emerging as an interesting angle from which to study how parasites have evolved sophisticated strategies to manipulate host gene transcription and protein expression. In this review, we discuss the application of an operational framework to investigate the host cell signalling pathways that are induced ...
Cheeseman, Kevin, Weitzman, Jonathan
openaire +2 more sources