Results 41 to 50 of about 4,226,477 (158)

Targeted Knockout of the Rickettsia rickettsii OmpA Surface Antigen Does Not Diminish Virulence in a Mammalian Model System

mBio, 2015
Strains of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever (RMSF), differ dramatically in virulence despite >99% genetic homology.
Nicholas F. Noriea, Tina R. Clark, Ted Hackstadt   +2 more
doaj   +1 more source

Discovery of RUF6 ncRNA–interacting proteins involved in P. falciparum immune evasion

Life Science Alliance, 2023
An RNA-directed proteomic discovery (ChIRP-MS) protocol is used to identify in vivo RUF6 ncRNA–protein interactions that sustain virulence genes in the human malaria parasite, Plasmodium falciparum .
Gretchen M Diffendall, Anna Barcons-Simon, Sebastian Baumgarten, Florent Dingli, Damarys Loew, Artur Scherf   +5 more
doaj   +1 more source

Pathological and ecological host consequences of infection by an introduced fish parasite [PDF]

, 2011
The infection consequences of the introduced cestode fish parasite Bothriocephalus acheilognathi were studied in a cohort of wild, young-of-the-year common carp Cyprinus carpio that lacked co-evolution with the parasite.
Pegg Josephine, Williams Chris F., Britton J. Robert, Pegg, Josie, J. Robert Britton, Britton, J.R., Chris F Williams, Josephine Pegg, J Robert Britton, Williams, C.F., Chris F. Williams   +10 more
core   +2 more sources

Functional Characterization of the m ⁶ A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite

mBio, 2021
Infection with the unicellular eukaryotic pathogen Plasmodium ...
Ameya Sinha, Sebastian Baumgarten, Amy Distiller, Emma McHugh, Patty Chen, Meetali Singh, Jessica M. Bryant, Jiaqi Liang, Germano Cecere, Peter C. Dedon, Peter R. Preiser, Stuart A. Ralph, Artur Scherf   +12 more
doaj   +1 more source

Life-history responses, transmission dynamics and epidemiology in a terrestrial gastropod infected with parasitic mites [PDF]

, 2010
Parasites are known to influence the life-history of their hosts. A parasite-induced reduction in host fecundity and survival may lead to a reduced rate of increase in the host population.
Schüpbach, Hans Ulrich
core   +1 more source

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum

mBio, 2018
Strains of Rickettsia rickettsii, the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain ...
Stephanie S. Lehman, Nicholas F. Noriea, Karin Aistleitner, Tina R. Clark, Cheryl A. Dooley, Vinod Nair, Simran Jeet Kaur, M. Sayeedur Rahman, Joseph J. Gillespie, Abdu F. Azad, Ted Hackstadt   +10 more
doaj   +1 more source

Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum

Open Research Europe, 2022
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in ...
Sebastian Baumgarten, Jessica Bryant
doaj   +1 more source

Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection [PDF]

, 2010
The postgenomic era has revolutionized approaches to defining host-pathogen interactions and the investigation of the influence of genetic variation in either protagonist upon infection outcome.
C. Michael R. Turner, Chan, Chi N, Tait, Andy, Andy Tait, Morrison, L.J., McLellan, Sarah, Turner, C Michael R, Sweeney, Lindsay, Chan, C.N., Liam J. Morrison, Annette MacLeod, Sweeney, L., Turner, C.M.R., Morrison, Liam J; id_orcid, Lindsay Sweeney, Chi N. Chan, Tait, A., Sarah McLellan, MacLeod, A., McLellan, S., MacLeod, Annette   +20 more
core   +1 more source

Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

International Journal for Parasitology: Drugs and Drug Resistance, 2016
The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal
Maeghan O'Neill, Cristina Ballesteros, Lucienne Tritten, Erica Burkman, Weam I. Zaky, Jianguo Xia, Andrew Moorhead, Steven A. Williams, Timothy G. Geary   +8 more
doaj   +1 more source

Current Treatments to Control African Trypanosomiasis and One Health Perspective

Microorganisms, 2022
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei.
Alberto Venturelli, Lorenzo Tagliazucchi, Clara Lima, Federica Venuti, Giulia Malpezzi, George E. Magoulas, Nuno Santarem, Theodora Calogeropoulou, Anabela Cordeiro-da-Silva, Maria Paola Costi   +9 more
doaj   +1 more source