Results 131 to 140 of about 5,241 (151)
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Detection of Alzheimer's Disease with Diffusion Tensor Imaging and Deformation-Based Morphometry
2011Novel MRI based acquisition and analysis techniques are increasingly used as biomarkers to discriminate between Alzheimer's disease and normal aging. Evaluating the diagnostic utility of the various approaches in use is difficult though because of significant methodological differences between studies.
Friese, Uwe +5 more
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Deformation‐based nuclear morphometry: Capturing nuclear shape variation in HeLa cells
Cytometry Part A, 2007AbstractThe empirical characterization of nuclear shape distributions is an important unsolved problem with many applications in biology and medicine. Numerous genetic diseases and cancers have alterations in nuclear morphology, and methods for characterization of morphology could aid in both diagnoses and fundamental understanding of these disorders ...
Gustavo K, Rohde +3 more
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Deformation Based Morphometry Analysis of Serial Magnetic Resonance Images of Mouse Brains
2006Deformation based morphometry is used to detect differences in in-vivo Magnetic Resonance Image (MRI) of the mouse brain obtained from two transgenic strains: TASTPM mice that over-express proteins associated with Alzheimer's disease, and wild-type mice. MRI was carried out at four time points.
Satheesh Maheswaran +9 more
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Neuroscience Letters, 2011
Twin studies are one of the most powerful study designs for estimating the relative contribution of genetic and environmental influences on phenotypic variation inhuman brain morphology. In this study, we applied deformation based morphometry, a technique that provides a voxel-wise index of local tissue growth or atrophy relative to a template brain ...
Uicheul, Yoon +3 more
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Twin studies are one of the most powerful study designs for estimating the relative contribution of genetic and environmental influences on phenotypic variation inhuman brain morphology. In this study, we applied deformation based morphometry, a technique that provides a voxel-wise index of local tissue growth or atrophy relative to a template brain ...
Uicheul, Yoon +3 more
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2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
This paper describes an approach to fine scale non-rigid registration for mapping patterns of tissue volume loss in serial MRI studies of the brain. Specifically it addresses the important confound of diffuse tissue contrast changes which can influence local sub-voxel estimates of volume change.
Colin, Studholme +2 more
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This paper describes an approach to fine scale non-rigid registration for mapping patterns of tissue volume loss in serial MRI studies of the brain. Specifically it addresses the important confound of diffuse tissue contrast changes which can influence local sub-voxel estimates of volume change.
Colin, Studholme +2 more
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Thalamic Morphometry Abnormalities in Trigeminal Neuralgia Using Deformation-Based Shape Analysis
ISMRM Annual MeetingMotivation: The potential pathophysiologic mechanisms related to trigeminal neuralgia (TN) needed elucidation, and alternative biomarkers of TN needed to be identified. Goal(s): To explore atrophy in specific subregions of the thalamus, which may contribute to the pathophysiology of TN.
Siping Luo +4 more
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AJNR. American journal of neuroradiology, 2007
Most previous neuroimaging studies of attention-deficit/hyperactivity disorder (ADHD) rely on the manual delineation of the region of interest, which is subjective and lacks reproducibility. The purpose of this study was to use an automated method to assess whether there are abnormalities in the brains of patients with ADHD.
Wang, J., Jiang, T., Cao, Q., Wang, Y.
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Most previous neuroimaging studies of attention-deficit/hyperactivity disorder (ADHD) rely on the manual delineation of the region of interest, which is subjective and lacks reproducibility. The purpose of this study was to use an automated method to assess whether there are abnormalities in the brains of patients with ADHD.
Wang, J., Jiang, T., Cao, Q., Wang, Y.
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Comparing voxel- and deformation-based morphometry in pediatric ADHD
JoCN ForumConnor Watkinson, Michelle Y. Kibby
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