Results 1 to 10 of about 497,953 (316)

Advances and limitations for the treatment of spinal muscular atrophy

BMC Pediatrics, 2022
Spinal muscular atrophy (5q-SMA; SMA), a genetic neuromuscular condition affecting spinal motor neurons, is caused by defects in both copies of the SMN1 gene that produces survival motor neuron (SMN) protein.
John W. Day, Kelly Howell, Amy Place, Kimberly Long, Jose Rossello, Nathalie Kertesz, George Nomikos   +6 more
doaj   +1 more source

Muscle metabolic stress determines cancer cachexia severity in mice

Frontiers in Physiology, 2022
Objectives: To determine the metabolic effects of cancer-conditioned media on myotube metabolism and to understand whether the variability of these effects is associated with cancer cachexia progression.Materials and methods: We established single-cell ...
Christiano Alves, Christiano Alves, Laurie Goodyear, Patricia Brum   +3 more
doaj   +1 more source

Correlation of brain segmental volume changes with clinical parameters: a longitudinal study in multiple sclerosis patients

Arquivos de Neuro-Psiquiatria, 2023
Objective To measure the cranial volume differences from 15 different parts in the follow-up of relapsing-remitting multiple sclerosis (RRMS) patients and correlate them with clinical parameters.
Neslihan Eskut, Ali Murat Koc, Asli Koskderelioglu, Ismail Dilek, Mustafa Agah Tekindal   +4 more
doaj   +1 more source

Hemifacial atrophy [PDF]

Dermatology Online Journal, 2013
We report the case of a 44-year-old woman with a one-year history of en coup de sabre morphea and progressive hemifacial atrophy with ipsilateral hemifacial neuralgia, migraine, and contralateral neurologic abnormalities. While rare, Parry-Romberg syndrome typically presents in the first or second decade of life; this patient's case is unusual in that ...
Vedvyas, Chetan, Urbanek, Richard W
openaire   +4 more sources

Caffeine Restores Neuronal Damage and Inflammatory Response in a Model of Intraventricular Hemorrhage of the Preterm Newborn

Frontiers in Cell and Developmental Biology, 2022
Germinal matrix-intraventricular hemorrhage (GM-IVH) is the most frequent intracranial hemorrhage in the preterm infant (PT). Long-term GM-IVH-associated sequelae include cerebral palsy, sensory and motor impairment, learning disabilities, or ...
Pilar Alves-Martinez, Pilar Alves-Martinez, Isabel Atienza-Navarro, Isabel Atienza-Navarro, Maria Vargas-Soria, Maria Vargas-Soria, Maria Jose Carranza-Naval, Maria Jose Carranza-Naval, Maria Jose Carranza-Naval, Carmen Infante-Garcia, Carmen Infante-Garcia, Isabel Benavente-Fernandez, Isabel Benavente-Fernandez, Isabel Benavente-Fernandez, Angel Del Marco, Angel Del Marco, Simon Lubian-Lopez, Simon Lubian-Lopez, Monica Garcia-Alloza, Monica Garcia-Alloza   +19 more
doaj   +1 more source

MRI Findings of Muscle Damage after Total Hip Arthroplasty Using the Complete Muscle Preserving Anterolateral Supine Approach

Medicina, 2022
Background and Objectives: We performed anterolateral total hip arthroplasty (ALS THA) with the purpose of complete muscle-tendon preservation without muscle-tendon dissection.
Shuhei Oda, Takashi Hisatome, Eiji Cho, Hirohisa Fujimaki, Kazuyoshi Nakanishi   +4 more
doaj   +1 more source

Long-Term Effects of Helicobacter pylori Eradication on Metachronous Gastric Cancer Development

Gut and Liver, 2018
Background/AimsGastric mucosal atrophy and intestinal metaplasia due to Helicobacter pylori infection are the main precursor lesions of gastric cancer. The aim of this study was to evaluate the long-term effects of H.
Seung Jun Han, Sang Gyun Kim, Joo Hyun Lim, Ji Min Choi, Sooyeon Oh, Jae Yong Park, Jung Kim, Joo Sung Kim, Hyun Chae Jung   +8 more
doaj   +1 more source

PTEN‐AKT pathway attenuates apoptosis and adverse remodeling in ponatinib‐induced skeletal muscle toxicity following BMP‐7 treatment

Physiological Reports, 2023
Tyrosine kinase inhibitors (TKIs) including ponatinib are commonly used to treat cancer patients. Unfortunately, TKIs induce cardiac as well as skeletal muscle dysfunction as a side effect.
Ayushi Srivastava, Dinender K. Singla
doaj   +1 more source

The cytological component of cervical cancer screening: causes of false negative and false positive results, and ways to avoid them

Репродуктивная эндокринология, 2021
Cervical cancer (CC) screening is a major component of secondary prevention of CC and involves screening all women at risk of developing this disease, most of whom are asymptomatic.
O.A. Burka, N.F. Lygyrda, V.V. Kutsovol, A.V. Svintsitska   +3 more
doaj   +1 more source

Risk Factors for Gastric Tumorigenesis in Underlying Gastric Mucosal Atrophy

Gut and Liver, 2017
Background/AimsAtrophic gastritis is considered a premalignant lesion. We aimed to evaluate the risk factors for gastric tumorigenesis in underlying mucosal atrophy.Methods : A total of 10,185 subjects who underwent upper gastrointestinal endoscopy ...
Ji Hyun Song, Sang Gyun Kim, Eun Hyo Jin, Joo Hyun Lim, Sun Young Yang   +4 more
doaj   +1 more source