Results 31 to 40 of about 556,819 (308)

Amygdala volume changes as a potential marker of multiple sclerosis progression: links to EDSS scores and PIRA

Frontiers in Immunology
IntroductionBrain atrophy may be a promising marker of relapsing-remitting multiple sclerosis (RRMS) progression, yet it remains underutilized in clinical practice.
Aleksandra Pogoda-Wesołowska, Ignacy Stachura, Nina Sługocka, Marta Kania-Pudło, Jacek Staszewski, Adam Stępień   +5 more
doaj   +1 more source

The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]

, 2012
Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
Bartlett, Jonathan W, Macdonald, Kate E, Leung, Kelvin K, ADNI investigators, Barnes, Josephine, Ourselin, Sebastien, Bartlett, JW, Ourselin, S, Macdonald, KE, Barnes, J, Leung, KK   +10 more
core   +1 more source

Development of Semi-Automated Image-Based Analysis Tool for CBCT Evaluation of Alveolar Ridge Changes After Tooth Extraction

Bioengineering
Following tooth extraction, the bone structure is prone to atrophic changes. Alveolar ridge resorption can compromise subsequent implant treatment not only at the extraction site itself but also by affecting the bone support of adjacent teeth.
Anja Heselich, Joanna Śmieszek-Wilczewska, Louisa Boyo, Robert Sader, Shahram Ghanaati   +4 more
doaj   +1 more source

PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress

Antioxidants, 2022
Skeletal muscle atrophy is an important characteristic of cachexia, which can be induced by chemotherapy and significantly contributes to functional muscle impairment.
Xiaoguang Liu, Miaomiao Xu, Yang Yu, Yingjie Chen, Xinyu Weng, Lin Zhu   +5 more
doaj   +1 more source

Changes in intranuclear mobility of mature snRNPs provide a mechanism for splicing defects in spinal muscular atrophy [PDF]

, 2012
This work was funded by the Wellcome Trust (grant ID WT078810MA)It is becoming increasingly clear that defects in RNA metabolism can lead to disease. Spinal muscular atrophy (SMA), a leading genetic cause of infant mortality, results from insufficient ...
Clelland, Allyson Kara, Bales, Alexandra Beatrice Elizabeth, Sleeman, Judith Elizabeth   +2 more
core   +1 more source

The Use of Dixon Magnetic Resonance Imaging Methods for the Quantification of Rotator Cuff Fatty Infiltration: A Systematic Review

Muscles
Fatty infiltration of the rotator cuff muscles is very common following rotator cuff tears and is one of the most important factors in determining treatment.
Andrew J. Nasr, Joshua Harris, Jijia Wang, Michael Khazzam, Nitin B. Jain, Yi-Ting Tzen, Yen-Sheng Lin   +6 more
doaj   +1 more source

Assessment of the impact of reconstitution therapies—cladribine tablets and alemtuzumab—on the atrophy progression among patients with relapse-remitting multiple sclerosis

Frontiers in Neuroscience
IntroductionImmune reconstitution therapies (IRT) are highly effective therapies for multiple sclerosis (MS). Among IRT, we can distinguish partially selective therapies such as cladribine in tablets (CLAD) and non-selective therapies, which include ...
Aleksandra Pogoda-Wesołowska, Ignacy Stachura, Arkadiusz Zegadło, Marzena Maciągowska-Terela, Karolina Sobolewska, Aleksander Dębiec, Jacek Staszewski, Adam Stępień   +7 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Structural MRI [PDF]

, 2011
Clinical neuroimaging is increasingly being used in the diagnosis of neurodegenerative diseases and has become one of the most important paraclinical tools in the diagnosis of dementia.
Wattjes, M.P., Mike P. Wattjes
core   +1 more source

Impact of α-synuclein fibril structure on seeding activity in experimental models of Parkinson’s disease

npj Parkinson's Disease
The central pathogenesis of Parkinson’s disease involves the misfolding and aggregation of α-synuclein (α-syn). There is a widespread belief that α-syn can propagate in a prion-like manner, and α-syn preformed fibrils (PFFs) have been widely used to ...
Junichiro Ohira, Masanori Sawamura, Kenichi Kawano, Risa Sato, Tomoyuki Taguchi, Tomoyuki Ishimoto, Jun Ueda, Masashi Ikuno, Shu-ichi Matsuzawa, Katsumi Matsuzaki, Ryosuke Takahashi, Hodaka Yamakado   +11 more
doaj   +1 more source