Comparison of prefrontal atrophy and episodic memory performance in dysexecutive Alzheimer’s disease and behavioural-variant frontotemporal dementia [PDF]
, 2016 Alzheimer’s disease (AD) sometimes presents with prominent executive dysfunction and associated prefrontal cortex atrophy. The impact of such executive deficits on episodic memory performance as well as their neural correlates in AD, however, remains ...
Alvarez +63 more
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Interleukin-17A promotes parietal cell atrophy by inducing apoptosis [PDF]
, 2018 Background & Aims: Atrophic gastritis caused by chronic inflammation in the gastric mucosa leads to the loss of gastric glandular cells, including acid-secreting parietal cells.
Alderuccio +47 more
core +3 more sources
Frontiers in Neurology, 2020 Cerebellar damage occurs frequently in multiple sclerosis (MS) patients, with a wide exhibition of symptoms particularly as impairments of balance and gait. Recent studies implementing new postprocessing magnetic resonance imaging (MRI) techniques showed
Serena Ruggieri +10 more
doaj +1 more source
Current evidence for treatment with nusinersen for spinal muscular atrophy : a systematic review [PDF]
, 2019 Recent discovery of nusinersen, an antisense oligonucleotide drug, has provided encouragement for improving treatment of spinal muscular atrophy. No therapeutic options currently exist for this autosomal recessive motor neuron disorder.
Meylemans, Antoon, De Bleecker, Jan
core +1 more source
Relationship between hippocampal structure and memory function in elderly humans [PDF]
, 2006 With progressing age, the ability to recollect personal events declines, whereas familiarity-based memory remains relatively intact. It has been hypothesized that age-related hippocampal atrophy may contribute to this pattern because of its critical role
A. Szentkuti +8 more
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The Effect of Chronic Exposure with Imidacloprid Insecticide on Fertility in Mature Male Rats [PDF]
International Journal of Fertility and Sterility, 2010 Background This study was conducted to evaluate the effect of chronic exposure to imidacloprid (IM) insecticide on male testicular tissue, sperm morphology and testosterone levels in the serum of mature male rats.
Golamreza Najafi +4 more
doaj +1 more source
, 2018 Quantifying the degree of atrophy is done clinically by neuroradiologists following established visual rating scales. For these assessments to be reliable the rater requires substantial training and experience, and even then the rating agreement between ...
Cavallin, Lena +6 more
core +1 more source
The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]
, 2012 Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
ADNI investigators +5 more
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Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice
Biomedicines, 2020 Glucocorticoids promote muscle atrophy by inducing a class of proteins called atrogenes, resulting in reductions in muscle size and strength.
Laura C. Gunder +6 more
doaj +1 more source
Withaferin A and Ovarian Cancer Antagonistically Regulate Skeletal Muscle Mass
Frontiers in Cell and Developmental Biology, 2021 Cachexia is a complex wasting syndrome that overwhelmingly affects the majority of late-stage cancer patients. Additionally, there are currently no efficacious therapeutic agents to treat the muscle atrophy induced by the cancer.
Alex R. Straughn +3 more
doaj +1 more source