Results 51 to 60 of about 495,366 (291)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Evolution of deformations in medium-mass nuclei

, 2005
Evolution of quadrupole deformations in $sd$ and $pf$ shell nuclei with mass A= 18$\sim$56 is studied by using deformed Skyrme Hartree-Fock (HF) model with pairing correlations. We point out that the quadrupole deformations of the nuclei with the isospin
A. Bohr, H. A. Jahn, H. Sagawa, I. Ragnarsson, I. Ragnarsson, K. Yamada, T. Suzuki, X. R. Zhou, X. Z. Zhang   +8 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

SOME FEATURES OF ATMOSPHERIC-LITHOSPHERIC OBSERVATIONS OF ACOUSTIC EMISSION AT «KARYMSHINA» SITE IN KAMCHATKA

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2019
The results of complex observations of acoustic emission in the near surface rocks and by the ground surface in the atmosphere are presented. The observation instrumentation includes a laser strainmeter-interferometer and a microbarometer installed in ...
I. A. Larionov, Yu.V. Marapulets
doaj   +1 more source

Deformations of Calabi-Yau hypersurfaces arising from deformations of toric varieties

, 2003
There are easy "polynomial" deformations of Calabi-Yau hypersurfaces in toric varieties performed by changing the coefficients of the defining polynomial of the hypersurface. In this paper, we explicitly constructed the ``non-polynomial'' deformations of
Altmann, Anvar R. Mavlyutov, Batyrev, Batyrev, Candelas, Cox, Danilov, Demazure, Katz, Mavlyutov, Mavlyutov, Mavlyutov, Ran, Todorov   +13 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Ricci-flat supertwistor spaces

, 2006
We show that supertwistor spaces constructed as a Kahler quotient of a hyperkahler cone (HKC) with equal numbers of bosonic and fermionic coordinates are Ricci-flat, and hence, Calabi-Yau.
A. Neitzke, A. Swann, A.D. Popov, B. de Wit, J. Park, L. Anguelova, L.J. Mason, M. Kulaxizi, M. Rocek, M. Rocek, Martin Rocek, R. Roiban, R.S. Ward, Rikard von Unge, Ulf Lindström   +14 more
core   +2 more sources

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source