Results 51 to 60 of about 220,330 (298)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
A mesh free model for plant tissue deformations during drying [PDF]
, 2014 Plant tissue has a complex cellular structure which is an aggregate of individual cells bonded by middle lamella. During drying process, plant tissues undergoes extreme deformations which mainly driven by moisture removal and turgor loss.
Senadeera, W. +3 more
core +1 more source
PBW deformations and quiver GIT for noncommutative resolutions [PDF]
, 2015 In this thesis we first investigate PBW deformations of Koszul, Calabi-Yau algebras, and we then study moduli spaces of representations of algebras defined by tilting bundles.
Karmazyn, Joseph Harry
core +3 more sources
Stress-deformed state of the Earth crust of the Bug mining area in the section Gayvoron—Zavalye
Геофизический журнал, 2018 Results of tectonic-physical studies of the upper part of the Earth mantle of the Bug mining area of the Bug block of the Ukrainian shield fulfilled in 2017 in the basin of the upper and middle course of the Southhern Bug river have been presented in ...
S. V. Mychak +3 more
doaj +1 more source
Computing Versal Deformations of Singularities with Hauser's Algorithm.
, 2013 Hauser’s algorithm provides an alternative approach to the computation of versal deformations, not based on step by step extending infinitesimal deformations.
Stevens, Jan, Jan Stevens, Stevens, Jan,
core +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Pathological Deformations of Brain Vascular System Modelling Using Analogous Eletromagnetic Systems
Advances in Electrical and Electronic Engineering, 2004 The contribution deals with the modelling and simulation of human brain haemodynamics using analogous electromagnetic systems characteristic especially propagation properties of distributed parameters circuits.
Klara Capova, Vladimir Blazek, Ivo Cap
doaj