Results 51 to 60 of about 229,975 (300)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Sceliphron deforme subsp. deforme
, 2021 Published as part of Anagha, S., Kumar, P. Girish, Binoy, C., Mazumdar, P. C. & Sureshan, P. M., 2021, A review of the mud-dauber wasps of genus Sceliphron Klug (Hymenoptera Sphecidae) from India, pp.
Anagha, S. +4 more
openaire +2 more sources
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Calabi-Yau Foliations and Deformations [PDF]
We propose in this article the study of the deformations of a Calabi-Yau type foliations F. For three different types of deformations (unfoldings, holomorphic, transversally holomorphic) there exist Kuranishi spaces K f , K h , K tr parametrizing the ...
Danain-Bertoncini, Rémi
core +3 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Physical Review D, 2002 We introduce a method to obtain deformed defects starting from a given scalar field theory which possesses defect solutions. The procedure allows the construction of infinitely many new theories that support defect solutions, analytically expressed in terms of the defects of the original theory. The method is general, valid for both topological and non-
Bazeia, D. +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Stress-deformed state of the Earth crust of the Bug mining area in the section Gayvoron—Zavalye
Геофизический журнал, 2018 Results of tectonic-physical studies of the upper part of the Earth mantle of the Bug mining area of the Bug block of the Ukrainian shield fulfilled in 2017 in the basin of the upper and middle course of the Southhern Bug river have been presented in ...
S. V. Mychak +3 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source