Results 61 to 70 of about 48,390 (294)

“Nature Made Us This Way…”: Crime without Punishment? (Fyodor Dostoevsky and Ivan Bunin). Article 2: “Are There Such Signs at Birth?” [PDF]

open access: yesДостоевский и мировая культура: Филологический журнал
The article examines the thesis of marginal anthropology as represented by Fyodor Dostoevsky in the novel Crime and Punishment and creatively reinterpreted by Ivan Bunin in the short story “Loopy Ears,” under the influence of the achievements of the ...
Gennady Yu. Karpenko
doaj   +1 more source

On Breaking Cosmic Degeneracy [PDF]

open access: yesThe Astrophysical Journal, 1998
It has been argued that the power spectrum of the anisotropies in the Cosmic Microwave Background (CMB) may be effectively degenerate, namely that the observable spectrum does not determine a unique set of cosmological parameters. We describe the physical origin of this degeneracy and show that at small angular scales it is broken by gravitational ...
Benton Metcalf R., Silk J.
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Orbital Degeneracy Loci II: Gorenstein Orbits

open access: yes, 2020
In [3] we introduced orbital degeneracy loci as generalizations of degeneracy loci of morphisms between vector bundles. Orbital degeneracy loci can be constructed from any stable subvariety of a representation of an algebraic group. In this paper we show
Manivel L.   +3 more
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Degeneracy in the Blasius problem

open access: yesElectronic Journal of Differential Equations, 2007
The Navier-Stokes equations for the boundary layer are transformed, by a similarity transformation, into the ordinary Blasius differential equation which, together with appropriate boundary conditions constitutes the Blasius problem, $$ f'''(
Faiz Ahmad
doaj  

Degeneracy in Heteroscedastic Regression Models [PDF]

open access: yes, 2000
The maximum likelihood estimation in a regression model with heteroscedastic errors is considered. When the design matrices in the model are inappropriately specified, the maximum likelihood estimates of the variances of certain observations are found to
Chan, Nai Ng, Li, Kim-Hung
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Sharp viscous shock waves for relaxation model with degeneracy

open access: yesAdvances in Nonlinear Analysis
This article is concerned with a relaxation model with degeneracy. Different from the existing studies on the regular viscous shock waves, we recognize that when the sub-characteristic condition is degenerate, the dynamical system possesses sharp viscous
Xu Shufang   +3 more
doaj   +1 more source

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