Results 141 to 150 of about 40,292 (276)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Multi‐Responsive Bowl‐Shaped Janus Nanomotors Based on Polyitaconic acid/Polypyrrole on the Surface of Iron Oxide Nanoparticles with Chemical, Electrical, and Magnetic Field Actuation for Targeted Drug Delivery Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi   +3 more
wiley   +1 more source

Global entropy solutions to a degenerate parabolic–parabolic chemotaxis system for flux-limited dispersal

open access: yesNonlinear Analysis: Real World Applications
Existence of global finite-time bounded entropy solutions to a parabolic-parabolic system proposed in [16] is established in bounded domains under no-flux boundary conditions for nonnegative bounded initial data. This modification of the classical Keller-Segel model features degenerate diffusion and chemotaxis that are both subject to flux-saturation ...
openaire   +4 more sources

Phase Space Electronic Structure Theory: From Diatomic Lambda-Doubling to Macroscopic Einstein-de Haas. [PDF]

open access: yesJ Phys Chem Lett
Peng L   +7 more
europepmc   +1 more source

The Role of Intraparticle Diffusion in Kinetic Model Discrimination: Proof of Concept Testing for Methanol Dehydration

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The rate of a heterogeneous catalytic process may simultaneously be described by several rate equations. In this case, discrimination between the plausible kinetic models is required. An intrinsic kinetic model of a heterogeneous catalytic process may successively be discriminated by the transition from a reaction rate‐limited regime to an ...
Oleksii Zhokh   +2 more
wiley   +1 more source

Emergent Spin Hall Quantization and High‐Order van Hove singularities in Square‐Octagonal MA2Z4

open access: yesAdvanced Physics Research, EarlyView.
Square‐octagonal MA2Z4 (M = Mo/W, A = Si/Ge, Z = pnictogen) monolayers are predicted to realize quantum spin Hall insulators with nearly quantized spin Hall conductivity enabled by an emergent spin U(1) quasi‐symmetry. Materials with Z = As and Sb host quasi‐flat bands with high‐order van Hove singularities near the Fermi level, making them promising ...
Rahul Verma   +3 more
wiley   +1 more source

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