Results 181 to 190 of about 1,369,784 (332)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Correction: mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence through regulating the sodium channel Scn1a

Bone Research, 2023
Ajuan Chen, Jian Jin, Shasha Cheng, Zezheng Liu, Cheng Yang, Qingjing Chen, Wenquan Liang, Kai Li, Dawei Kang, Zhicong Ouyang, Chenfeng Yao, Xiaochun Bai, Qingchu Li, Dadi Jin, Bin Huang   +14 more
doaj   +1 more source

Degeneration-Driven and Load-Modulated Fluid-Driven Viscoelasticity of the Human Intervertebral Disc: A Probabilistic Biphasic Swelling Modeling Study. [PDF]

Bioengineering (Basel)
Sun Z, Dang Y, Mi C, Gu J, Pan J.
europepmc   +1 more source

“Degeneration” in Dermatopathology

Indian Journal of Dermatology, Venereology and Leprology, 2023
Abhishek R, Parekh, Hiral A, Shah
openaire   +2 more sources

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Physical activity and the risk of cataract and age-related macular degeneration: a systematic review and meta-analysis of cohort studies. [PDF]

BMC Ophthalmol
Aune D, Jayedi A, Kazemi A, Soltani S, Rezaei F, Leitzmann MF.   +5 more
europepmc   +1 more source

Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration

Science, 2005
J. Haines, M. Hauser, S. Schmidt, W. Scott, L. Olson, P. Gallins, Kylee L. Spencer, S. Y. Kwan, M. Noureddine, J. Gilbert, N. Schnetz-Boutaud, A. Agarwal, E. Postel, M. Pericak-Vance   +13 more
semanticscholar   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

The Degeneration Paradox: Severely Degenerated Cervical Nucleus Pulposus Cells Display Enhanced Mechanoplasticity Under Moderate Cyclic Tensile Strain. [PDF]

Biomolecules
Wang Y, Chen Y, Xiao B, Zhang B, Huang J, Zhang N, Wu B, Rong T, Liu B.   +8 more
europepmc   +1 more source

Programmed axon degeneration: from mouse to mechanism to medicine

Nature Reviews Neuroscience, 2020
M. Coleman, A. Höke
semanticscholar   +1 more source