Background/objectives To investigate the association between optical coherence tomography (OCT) markers of lesion activity and changes in visual acuity (VA) during anti-vascular endothelial growth factor (anti-VEGF) therapy of eyes diagnosed with ...
U. Chakravarthy+5 more
semanticscholar +1 more source
Severity of Spinal Cord Injury Influences Diffusion Tensor Imaging of the Brain [PDF]
Background: The purpose of this study was to determine whether DTI changes in the brain induced by a thoracic spinal cord injury are sensitive to varying severity of spinal contusion in rats. Methods: A control, mild, moderate, or severe contusion injury
Budde, Matthew D.+4 more
core +1 more source
Vasodilators, Blood Pressure-Lowering Medications, and Age-Related Macular Degeneration [PDF]
To examine the association of vasodilator and antihypertensive medication use with the incidence of age-related macular degeneration (AMD).Longitudinal population-based study.Persons 43 to 86 years of age living in Beaver Dam, Wisconsin, from 1988 through 1990.Examinations were performed every 5 years over a 20-year period. There were 9676 total person-
Ronald Klein+2 more
openaire +3 more sources
Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić+13 more
wiley +1 more source
The crosstalk between MYC and mTORC1 during osteoclastogenesis
Osteoclasts are bone-resorbing cells that undergo extensive changes in morphology throughout their differentiation. Altered osteoclast differentiation and activity lead to changes in pathological bone resorption.
Seyeon Bae+10 more
doaj +1 more source
Learning Global-Local Correspondence with Semantic Bottleneck for Logical Anomaly Detection [PDF]
This paper presents a novel framework, named Global-Local Correspondence Framework (GLCF), for visual anomaly detection with logical constraints. Visual anomaly detection has become an active research area in various real-world applications, such as industrial anomaly detection and medical disease diagnosis.
arxiv
Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis [PDF]
SummaryAnimal models of osteoarthritis (OA) are essential tools for investigating the development of the disease on a more rapid timeline than human OA.
A.A. Pitsillides+106 more
core +1 more source
EFFECT OF INTRAOCULAR PRESSURE–LOWERING MEDICATIONS ON NEOVASCULAR AGE-RELATED MACULAR DEGENERATION TREATMENT OUTCOMES IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENT TRIALS [PDF]
Purpose: To evaluate the effect of intraocular pressure-lowering medications on treatment outcomes in the Comparison of AMD Treatments Trials. Methods: Secondary analysis of Comparison of AMD Treatments Trials data.
Wei Pan+4 more
openaire +3 more sources
Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL
ABSTRACT Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of acute cerebral microinfarcts (ACMIs) in patients with CADASIL.
Xuejiao Men+11 more
wiley +1 more source
Impact-Induced Cartilage Damage Assessed using Polarisation-Sensitive Optical Coherence Tomography [PDF]
Significance: Non-invasive determination of structural changes in articular cartilage immediately after impact and rehydration provides insight into the response and recovery of the soft tissue, as well as provides a potential methodology for clinicians to quantify early degenerative changes. Approach: A custom-designed impact testing rig was used to
arxiv