Results 191 to 200 of about 4,732,020 (409)

Non-canonical functions of Telomerase Reverse Transcriptase – Impact on redox homeostasis

Redox Biology, 2020
Telomerase consists of the catalytic subunit Telomerase Reverse Transcriptase (TERT) and the Telomerase RNA Component. Its canonical function is the prevention of telomere erosion.
Julia Rosen, Philipp Jakobs, Niloofar Ale-Agha, Joachim Altschmied, Judith Haendeler   +4 more
doaj  

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Multifunctional nanomaterials via cell cuproptosis and oxidative stress for treating osteosarcoma and OS-induced bone destruction

Materials Today Bio
Reactive Oxygen Species (ROS) refers to a highly reactive class of oxidizing species that have the potential to induce cellular apoptosis and necrosis. Cuproptosis, a type of cell death, is primarily associated with the effects of copper ions.
Lin Ye, Congcong Yu, Jiechao Xia, Kainan Ni, Yejin Zhang, Xiaozhang Ying, Dingqi Xie, Yang Jin, Rongtai Sun, Ruikang Tang, Shunwu Fan, Shasha Yao   +11 more
doaj  

Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

Bioactive Materials, 2023
Injectable bone biomaterials like bone cement should be designed and fabricated with certain biological criteria, which include: 1) recruitment and polarization of the macrophages from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype, 2) enhance
Shuaijie Li, Liyan Zhang, Chunyu Liu, Jua Kim, Kun Su, Tingli Chen, Limin Zhao, Xiaomei Lu, Hao Zhang, Yinglin Cui, Xu Cui, Feng Yuan, Haobo Pan   +12 more
doaj  

Health And Economic Outcomes Related to Delay Between Medical Indication and Treatment With Ranibizumab In Age-Related Macular Degeneration In Greece [PDF]

, 2015
Georgia Kourlaba, M. Hatzikou, Γεωργία Παντελοπούλου, Nikos Maniadakis   +3 more
openalex   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Harnessing the power of longitudinal medical imaging for eye disease prognosis using Transformer-based sequence modeling [PDF]

arXiv
Deep learning has enabled breakthroughs in automated diagnosis from medical imaging, with many successful applications in ophthalmology. However, standard medical image classification approaches only assess disease presence at the time of acquisition, neglecting the common clinical setting of longitudinal imaging.
arxiv  

Inorganic Dielectric Materials Coupling Micro‐/Nanoarchitectures for State‐of‐the‐Art Biomechanical‐to‐Electrical Energy Conversion Devices

Advanced Materials, EarlyView.
Biomechanical‐to‐electrical energy conversion devices are uniquely suited for self‐driven physiological information monitoring and powering human–computer interaction systems. These devices based on micro‐/nanoarchitectured inorganic dielectric materials (MNIDMs) have shown ultrahigh electromechanical performance and thus great potential for practical ...
Jia‐Han Zhang, Zhengtong Li, Zeng Liu, Mingxuan Li, Jiaxin Guo, Jinhua Du, Changkun Cai, Shaohui Zhang, Ningning Sun, Yong Li, Xingtao Xu, Xihong Hao, Yusuke Yamauchi   +12 more
wiley   +1 more source

Specialized curricula for training vision-language models in retinal image analysis [PDF]

arXiv
Clinicians spend a significant amount of time reviewing medical images and transcribing their findings regarding patient diagnosis, referral and treatment in text form. Vision-language models (VLMs), which automatically interpret images and summarize their findings as text, have enormous potential to alleviate clinical workloads and increase patient ...
arxiv