Results 211 to 220 of about 4,732,020 (409)

A mechanical-assisted post-bioprinting strategy for challenging bone defects repair

open access: yesNature Communications
Bioprinting that can synchronously deposit cells and biomaterials has lent fresh impetus to the field of tissue regeneration. However, the unavoidable occurrence of cell damage during fabrication process and intrinsically poor mechanical stability of ...
Jirong Yang   +11 more
doaj   +1 more source

Learning Disease State from Noisy Ordinal Disease Progression Labels [PDF]

open access: yesarXiv
Learning from noisy ordinal labels is a key challenge in medical imaging. In this work, we ask whether ordinal disease progression labels (better, worse, or stable) can be used to learn a representation allowing to classify disease state. For neovascular age-related macular degeneration (nAMD), we cast the problem of modeling disease progression ...
arxiv  

Medical Prospect of Melatonin in the Intervertebral Disc Degeneration through Inhibiting M1-Type Macrophage Polarization via SIRT1/Notch Signaling Pathway [PDF]

open access: gold, 2023
Xinyu Dou   +8 more
openalex   +1 more source

Microfluidic Spinning of PEDOT:PSS Microfibers for Nerve Guidance Conduits

open access: yesAdvanced Materials Technologies, EarlyView.
This publication explores the fabrication of microfluidically spun PEDOT:PSS microfibers for conductive nerve guidance conduits (NGCs). It details the spinning process, fiber characterization, and biocompatibility assessment. The study highlights the fibers' mechanical and electrical properties, non‐cytotoxicity, and potential for nerve regeneration or
Matthias Geiger   +8 more
wiley   +1 more source

Structural insights into drug transport by an aquaglyceroporin

open access: yesNature Communications
Pentamidine and melarsoprol are primary drugs used to treat the lethal human sleeping sickness caused by the parasite Trypanosoma brucei. Cross-resistance to these two drugs has recently been linked to aquaglyceroporin 2 of the trypanosome (TbAQP2 ...
Wanbiao Chen   +10 more
doaj   +1 more source

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

open access: yesAdvanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló   +5 more
wiley   +1 more source

Long‐Term Study of Optical Nanoparticles Doped With Yb3+/Er3+ and Transition Metal Ions and their Real Application for Imaging and Temperature Sensing on Triticum Aestivum L.

open access: yesAdvanced Optical Materials, EarlyView.
This work shows a study on SrF2:Yb3+, Er3+ water colloid, additionally doped with transition metals (Sc3+ or Zn2+) to enhance observed emission, tested during 22 weeks of storage in ambient conditions. Due to high stability, excellent optical properties achieved under 975 nm excitation, and negligible phytotoxicity, the nanoparticles are applied for ...
Dominika Przybylska   +4 more
wiley   +1 more source

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