Results 231 to 240 of about 546,188 (282)

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park   +19 more
wiley   +1 more source

Assessing the Viability and Degeneration of the Medically Important Filarial Nematodes

open access: hybrid, 2017
Charles D. Mackenzie   +3 more
openalex   +2 more sources

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan   +12 more
wiley   +1 more source

Nanoscale Decoupling of Carrier–Phonon Transport in Carbon Nanotube–Halide Perovskite Heterostructures

open access: yesAdvanced Science, EarlyView.
Heterostructures of highly conductive single‐walled carbon nanotubes with low conductivity hybrid perovskites break the trade‐off between electrical and thermal conductivity. This design boosts electrical conductivity while significantly lowering thermal conductivity.
Md Azimul Haque   +13 more
wiley   +1 more source

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