Results 251 to 260 of about 546,188 (282)

Gender as Pathology: Disease, Degeneration, and Medical Discourse in Late Nineteenth-century Colombia

, 2012
Hanni Jalil Paier
openalex   +2 more sources

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Fatigue-induced biomechanical decoupling at L4-S1 discs: mechanism of disc degeneration in chronic low back pain. [PDF]

BMC Musculoskelet Disord
Xi X, Jia L, Yu W, Yu H, Qin Y, Tsai TY, Yu Y, Cheng L.   +7 more
europepmc   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen, Chenhao Che, Lingjie Wu, Changjie Sun, Dongming Xu, Qinyang Hua, Yunzhong Zhang, Yi‐Quan Tang, Peng Shi, Shan Sun   +9 more
wiley   +1 more source

Paraneoplastic Cerebellar Degeneration from Subclinical Breast Cancer on Mammography. [PDF]

JMA J
Sasada S, Kawamata A.
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Intermittent fasting attenuates glial hyperactivation and photoreceptor degeneration in a NaIO₃-induced mouse model of age-related macular degeneration. [PDF]

Commun Biol
Li J, Wang B, Liu P, Qiu X, Bian Q, Shen C, Li Y, Shao M, Li M.   +8 more
europepmc   +1 more source

Switchable Bidirectional Sound Absorption Via Exceptional Point Modulation in Acoustic Metastructures with Interleaved Resonator Coupling

Advanced Science, EarlyView.
A switchable bidirectional acoustic metastructure is proposed, enabling broadband and frequency‐selective absorption via interleaved resonator coupling and exceptional point modulation. It outperforms traditional unidirectional designs, offering compact, efficient sound control from both directions and establishing a generalized framework for extending
Zichao Guo, Liangfen Du, Zirui Yang, Kexin Zeng, Ziping Lei, Zhonggang Wang, Zhendong Li, Zheng Fan   +7 more
wiley   +1 more source