Results 281 to 290 of about 549,632 (363)

Letter to "Effect of Baseline Adjacent Segment Degeneration on Clinical Outcomes After Lumbar Fusion". [PDF]

Global Spine J
Wang Z, Zhao J, Qin X.
europepmc   +1 more source

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

Advanced Science, EarlyView.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu, Yubo Feng, Fei Hu, Xu Zheng, Yurun Ding, Xuesong Liu, Shicheng Huo, Zhuocheng Lyu   +7 more
wiley   +1 more source

Impact of Abnormal Mechanical Stress on Chondrocyte Death in Osteoarthritis. [PDF]

Med Sci Monit
Du J, Sun X, Ao L, Zhou X, Shi H, Yong Q, Zhang X, Guan T.   +7 more
europepmc   +1 more source

What\u27s new in spine surgery [PDF]

, 2003
Anderson, Paul A., Boden, Scott D., Bridwell, Keith H., Vaccaro, Alexander R., Zigler, Jack E.   +4 more
core   +2 more sources

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Systemic Lupus Erythematosus Exacerbates Hip Arthritis by Promoting Chondrocyte Pyroptosis in the Femoral Head via Activating the NF-κB Pathway. [PDF]

J Cell Mol Med
Fang X, Zhang H, Zhou H, Shen S, Lao Z, Zhang Z, Bian Y, Zhou C, Jin H, Tong P, Huang Y, Zhou H, Zeng H, Fu F, Wu C, Zheng W, Ruan H.   +16 more
europepmc   +1 more source

Enhancement of Optical Transparency and Electrical Conductivity of IZO/Ag/IZO Multilayer Film by Intense Pulsed Light and its Effect on the Photovoltaic Performances of Perovskite Solar Cells

Advanced Science, EarlyView.
The highly conductive IZO/Ag/IZO multilayer transparent electrode is successfully fabricated through flashlight annealing (FLA) process. A transient thermal effect of FLA maintains the continuous Ag interlayer and improves the crystallinity of the sandwich IZO layers. This combination increases both electric conductivity and optical transmittance.
Sumin Bae, Youngsoo Jung, Vishal Pal, Jung‐Kun Lee   +3 more
wiley   +1 more source

The Future of Motion Preservation and Arthroplasty in the Degenerative Lumbar Spine. [PDF]

J Clin Med
Pheasant MS, Parry MW, Girgis M, Tang A, Chen T.   +4 more
europepmc   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source