Results 31 to 40 of about 564,044 (302)

Morphometric analyses of the visual pathways in macular degeneration

open access: yes, 2014
Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated.
Baseler, Heidi A.   +8 more
core   +2 more sources

Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors

open access: yesNature Communications, 2021
Clinical evidence has established that concomitant traumatic brain injury (TBI) accelerates bone healing, but the underlying mechanism is unclear. This study shows that after TBI, injured neurons, mainly those in the hippocampus, release osteogenic ...
Wei Xia   +17 more
doaj   +1 more source

Functional Outcomes of the Low Vision Depression Prevention Trial in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Purpose: To compare the efficacy of behavioral activation (BA) plus low vision rehabilitation with an occupational therapist (OT-LVR) with supportive therapy (ST) on visual function in patients with age-related macular degeneration (AMD). Methods: Single-
Casten, Robin J.   +4 more
core   +3 more sources

Effect of daphnetin combined with tobramycin on Pseudomonas aeruginosa biofilm infection in vitro and in vivo

open access: yesFrontiers in Immunology
ObjectiveThe aim of this study was to investigate the effectiveness of daphnetin in combination with tobramycin on Pseudomonas aeruginosa biofilm infection in vitro and in vivo.MethodThe study was divided into four groups: control, tobramycin, daphnetin,
Dingbin Li   +10 more
doaj   +1 more source

Comparisons of the Efficacy and Safety of Total Knee Arthroplasty by Different Surgical Approaches: A Systematic Review and Network Meta‐analysis

open access: yesOrthopaedic Surgery, 2022
The purpose of this network meta‐analysis was to investigate the efficacy and safety of total knee arthroplasty (TKA) considering seven different surgical approaches.
Jin‐long Zhao   +7 more
doaj   +1 more source

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. [PDF]

open access: yes, 2019
Cognitive deficits are a devastating neurological outcome seen in survivors of cardiac arrest. We previously reported water electrolysis derived 67% hydrogen gas inhalation has some beneficial effects on short-term outcomes in a rat model of global brain
Alexander   +32 more
core   +2 more sources

Polyethylene microplastics trigger osteosarcoma progression via ITGA5/FAPα/LGMN cancer promoting complex: A novel environmental cancer promoting mechanism

open access: yesEcotoxicology and Environmental Safety
This study seeks to elucidate the molecular mechanisms by which polyethylene microplastics (PE-MPs) facilitate the progression of osteosarcoma through the modulation of the ITGA5/FAPα/LGMN protein complex.
Weilin Zhang   +9 more
doaj   +1 more source

The Role of Nrf2 in Hearing Loss

open access: yesFrontiers in Pharmacology, 2021
Hearing loss is a major unresolved problem in the world, which has brought a heavy burden to society, economy, and families. Hair cell damage and loss mediated by oxidative stress are considered to be important causes of hearing loss.
Dafei Li   +7 more
doaj   +1 more source

Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome. [PDF]

open access: yes, 2018
PurposeTo evaluate the relationship between retinal vascular caliber and AMD in patients with AIDS.MethodsParticipants enrolled in the Longitudinal Study of the Ocular Complications of AIDS had retinal photographs taken at enrollment.
Danis, Ronald P   +4 more
core   +1 more source

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

open access: yesEcotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang   +10 more
doaj   +1 more source

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