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STING signaling in inflammaging: a new target against musculoskeletal diseases

open access: yesFrontiers in Immunology, 2023
Stimulator of Interferon Gene (STING) is a critical signaling linker protein that plays a crucial role in the intrinsic immune response, particularly in the cytoplasmic DNA-mediated immune response in both pathogens and hosts.
Chenyu Song   +11 more
doaj   +1 more source

Mitophagy in degenerative joint diseases [PDF]

open access: yesAutophagy, 2020
Mitochondrial dysfunction is involved in aging and multiple degenerative diseases, including intervertebral disc degeneration (IVDD) and osteoarthritis (OA). Thus, the maintenance of mitochondria homeostasis and function is important. Mitophagy, a process that selectively clears damaged or dysfunctional mitochondria through autophagic machinery ...
Sun, Kai   +4 more
openaire   +2 more sources

Exosome-sheathed ROS-responsive nanogel to improve targeted therapy in perimenopausal depression

open access: yesJournal of Nanobiotechnology, 2023
The development of natural membranes as coatings for nanoparticles to traverse the blood-brain barrier (BBB) presents an effective approach for treating central nervous system (CNS) disorders.
Yue Hu   +9 more
doaj   +1 more source

Lesser metatarsophalangeal joint implant hemiarthroplasty: A case series highlighting treatment of degenerative joint disease in the lesser metatarsophalangeal joints

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases, 2023
There is currently a paucity of literature regarding treatment options of degenerative joint disease of the lesser metatarsophalangeal joints. Despite multiple treatment options available for degenerative joint disease of the 1st metatarsophalangeal ...
Kyle W. Abben, DPM   +3 more
doaj   +1 more source

GraXRS-Dependent Resistance of Staphylococcus aureus to Human Osteoarthritic Synovial Fluid

open access: yesmSphere, 2021
Osteoarthritis, a degenerative disease that results in the breakdown of joint cartilage and underlying bone, is the most prevalent joint disease in the United States.
David W. Watson   +3 more
doaj   +1 more source

Reconstruction of the mandibular condyle due to degenerative disease

open access: yesJournal of Oral Biology and Craniofacial Research, 2023
Degenerative joint disease (DJD), also known as osteoarthritis is the most common form of arthritis and can affect the temporomandibular joint (TMJ). TMJ DJD is characterized by degradation of the articular cartilage and synovial tissues resulting in ...
Nicholas Wilken, Gary Warburton
doaj   +1 more source

CLINICAL, BIOCHEMICAL AND HISTOPATHOLOGICAL STUDIES ON ARTHRITIS IN EQUINE [PDF]

open access: yesVeterinary Medical Journal - Giza, 1994
Experimentally chemically induced arthritis was formed using single intra articular injection of 10 mg amphotncine B in left radiocarpal joint of 8 horses; 7 donkeys and 5 mules with normal joints. clinical examination; radiological examination; synovial
A HEGAZY   +4 more
doaj   +1 more source

OSTEOARTHRITIS: MANAGEMENT OF PATIENTS AND COMPLIANCE TO TREATMENT

open access: yesМедицинский совет, 2018
Osteoarthritis (syn: arthrosis, osteoarthritis, osteoarthritic disease, deforming osteoarthritis, degenerative arthropathy, degenerative-dystrophic joint disease, Kellgren’s disease, etc.) is a heterogeneous group of joint diseases of various etiology ...
V. V. Tsurko   +2 more
doaj   +1 more source

Multivariate analysis of pedicle screw invasion of the proximal facet joint after lumbar surgery

open access: yesBMC Musculoskeletal Disorders, 2022
Background To analyze the risk factors for pedicle screw invasion of the proximal facet joint after lumbar surgery. Methods From January 2019 to January 2021, 1794 patients with lumbar degenerative disease, such as lumbar disc herniation, lumbar spinal ...
Peng Tao Wang   +4 more
doaj   +1 more source

Nanomaterial-mediated antibiotic delivery: a novel strategy for osteomyelitis therapy

open access: yesFrontiers in Bioengineering and Biotechnology
Osteomyelitis is an inflammatory bone disease caused by bacterial infection, often leading to bone destruction and functional impairment. Traditional treatments face significant limitations, including substantial surgical trauma, low drug delivery ...
Shuang Cheng   +5 more
doaj   +1 more source

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