Results 31 to 40 of about 157,424 (307)

Alpinia officinarum Hance: a comprehensive review of traditional uses, phytochemistry, pharmacokinetic and pharmacology

Frontiers in Pharmacology
The dried root and rhizome of Alpinia officinarum Hance (A. officinarum) have been widely used in traditional Chinese medicine for thousands of years to alleviate pain, promote digestion, warm the stomach, and disperse cold.
Xia Lei, Jiapeng Wang, Jiapeng Wang, Kun Zuo, Tianli Xia, Jinfeng Zhang, Xiangyue Xu, Qing Liu, Xiaoliang Li   +8 more
doaj   +1 more source

Viscosupplementation in prevention and treatment of the degenerative joint disease

Studia Medyczne, 2016
Osteoarthritis (OA) is one of the most common musculoskeletal disorders. It limits patients’ functionality and life satisfaction significantly. Although there are numerous types of therapy, the success rate of conservative treatment is limited, and it is
Andrzej Kotela, Sylwia Sarzyńska, Maria Woźniak, Paweł Łęgosz, Małgorzata Starczyńska, Ireneusz Kotela   +5 more
doaj   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling

Journal of Orthopaedic Translation
Objectives: To investigate the potential role of Ribosomal protein L35 (RPL35) in regulating chondrocyte catabolic metabolism and to examine whether osteoarthritis (OA) progression can be delayed by overexpressing RPL35 in a mouse compression loading ...
Jinjian Zhu, Liangliang Liu, Rengui Lin, Xiongtian Guo, Jianbin Yin, Haoyu Xie, Yuheng Lu, Zhicheng Zhang, Hongbo Zhang, Zihao Yao, Haiyan Zhang, Xiangjiang Wang, Chun Zeng, Daozhang Cai   +13 more
doaj   +1 more source

Differential patterns of PMN-elastase and type III procollagen peptide in knee joint effusions due to acute and chronic sports injuries [PDF]

, 1991
In 38 traumatic knee joint effusions the proteolytic enzyme PMN-elastase (PMN-E) and the repair marker procollagen III aminoterminal peptide (PIIINP) were determined.
A Billing, AM Gressner, C Frank, DJ Prockop, EJ Campbell, G Faby, H Rohde, H. Fritz, HS Cheung, I Eckle, K Horslev-Petersen, K Horslev-Petersen, K Horslev-Petersen, K Kleesik, K Kuramitsu, K Mark von der, K. -A. Riel, LS Lohmander, M Hörl, M Jochum, M Jochum, M Rojkind, M. Jochum, ME Nimi, P. Bernett, R Timple, RA Sandhaus, S Gay, S Neumann, SE McGowan   +29 more
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Diacerein: A New Disease Modulating Agent in Osteoarthritis [PDF]

Indian Journal of Physical Medicine & Rehabilitation, 2007
Diacerein is a new anti-inflammatory analgesics and antipyretic drug, developed specially for the treatmentof osteoarthritis which is one of the most prevalent degenerative joint disease.
Medhi B, Singh PK, Prakash A, Sen R, Wadhwa S   +4 more
doaj  

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Patient Outcomes Following Hip and Knee Joint Replacement Surgery: Role of the Social and Physical Environment in Recovery [PDF]

, 2016
Osteoarthritis is a degenerative joint disease that affects over 27 million Americans (Centers for Disease Control & Prevention, 2014). Joint replacement surgery is often recommended for patients who do not respond to conventional medical treatment. Post-
Sampson, Brittany Anne
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source