Results 71 to 80 of about 6,731,159 (297)

Assessing the micromechanical architecture of joint tissues with speckle rheological microscopy

open access: yesNature Communications
Joint tissues rely on a finely tuned interplay between solid (elastic) and fluid (viscous) constituents to support their mechanical function. Degradation of these constituents due to disease or trauma disrupts the elastic and viscous susceptibility of ...
Nichaluk Leartprapun   +4 more
doaj   +1 more source

CONSIDERATIONS ON THE EFFICIENCY OF HYDROKINETOTHERAPY IN THE COMPLEX PROCESS OF FUNCTIONAL REHABILITATION OF THE KNEE OSTEOARTHRITIS [PDF]

open access: yesRomanian Journal of Physical Therapy, 2019
Osteoarthritis is associated with the presence of pain and activity limitation which makes it one of the major causes of disability. Therefore, this disease became not only an important challenge in healthcare, but also a major public health and socio ...
Ioan-Cosmin Boca, Emilian Tarcău
doaj  

The Degenerative Joint Disease – Morphological Aspects in the Wild Boar

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The aim of the study was to outline some data about the morphology of the pathological wild boar articular cartilage. The study was carried out on articular cartilage samples from wild boar femoral head and condyles, 1 - 10 years old.
Liliana Cărpinișan   +4 more
doaj  

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang   +16 more
wiley   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

open access: yesAdvanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang   +6 more
wiley   +1 more source

Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats

open access: yesBMC Veterinary Research, 2012
Background Available information suggests a mismatch between radiographic and orthopedic examination findings in cats with DJD. However, the extent of the discrepancy between clinical and radiographic signs of OA in companion animals has not been ...
Lascelles B Duncan X   +5 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Structural aspects of degenerative disease of the temporomandibular articulation

open access: yes, 1989
The authors, after having considered some structural aspects of the temporomandibular joint, examine the histologic features of the degenerative disease (arthrosis, remodelling, deviation in form)
PERA, PAOLO, E. Cardesi
core   +1 more source

Total ankle replacement from the lateral approach – assessment of pain intensity and function [PDF]

open access: yesChirurgia Narządów Ruchu i Ortopedia Polska
Introduction. Total ankle replacement (TAR) is a viable alternative for treating advanced-stage ankleosteoarthritis (OA). The lateral approach offers a good surgical option to the anterior approach, potentiallyinfluencing surgical techniques, implant ...
Henryk Liszka   +5 more
doaj   +1 more source

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