Results 51 to 60 of about 9,545 (215)

Functional outcome following direct repair or intervertebral fusion for adolescent spondylolysis : a systematic review [PDF]

, 2012
A systematic review of the literature was performed to establish whether direct repair of the pars defect or intervertebral fusion achieves better Oswestry Disability Index scores in adolescent spondylolysis or low-grade spondylolisthesis.
Cooke, Stephen J., Westacott, Daniel J.
core   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari, Mallory Pine, Viktoriya Sapkalova, Emily Chan Brodowsky, Charles R. Powell, Ramzy T. Burns   +5 more
wiley   +1 more source

Correlation between degenerative lumbar scoliosis and multifidus muscle degeneration

陆军军医大学学报, 2022
Objective To evaluate the lumbar multifidus muscle in patients with degenerative lumbar scoliosis (DLS) by magnetic resonance imaging (MRI), and to analyze the degeneration features of lumbar multifidus muscle in the convex and concave sides of different
YU Xueke, CHEN Can, LI Kai, CHEN Chunhua, HU Chenbo   +4 more
doaj   +1 more source

Conservative Treatment of Degenerative Lumbar Scoliosis

, 2021
Degenerative lumbar scoliosis (DLS) is commonly seen in people over the age of 50 years. The prevalence increases with age. Patients with DLS often complain of low back pain and radiculopathy. Neurological complaints are rare. Current treatments are generally targeted at pain relief.
openaire   +2 more sources

A Clinical Study of Degenerative Lumbar Scoliosis

Journal of the Korean Orthopaedic Association, 1992
There have been several epidemiologic studies showing that scoliosis is most common in the elderly over 50 years of age [1,2]. Vanderpool et al. reported that scoliotic curves in the elderly were due to osteoporosis or osteomalacia [3], but Robin found no direct correlation between the presence or progression of scoliosis and osteoporosis [2].
Myung-Sang Moon, Kyu-Sung Lee, Chong-In Lim, Young-Bum Kim, Heon-Sang Lee   +4 more
openaire   +1 more source

Musculoskeletal health among adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Christina M Marciniak, Maram Sofiany, Reuel Jalal, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms   +11 more
wiley   +1 more source

Hip-sacroiliac joint-spine syndrome in total hip arthroplasty patients

Scientific Reports
This study is designed to compare the extent of sacroiliac joint (SIJ) degeneration at total hip arthroplasty (THA) for two pathologies: osteoarthritis of the hip (OA) and osteonecrosis of the femoral head (ON).
Ayumi Kaneuji, Makoto Fukui, Eiji Takahashi, Yusuke Sanji, Hiroaki Hirata, Norio Kawahara   +5 more
doaj   +1 more source

Sagittal plane analysis of the spine and pelvis in degenerative lumbar scoliosis

Journal of Orthopaedic Surgery, 2017
Background: Previous studies have reported the normative values of pelvic sagittal parameters, but no study has analyzed the sagittal spino-pelvic alignment in degenerative lumbar scoliosis (DLS) and its role in the pathogenesis.
Fei Han, Li Weishi, Sun Zhuoran, Ma Qingwei, Chen Zhongqiang   +4 more
doaj   +1 more source