Results 71 to 80 of about 9,545 (215)

Generalized Joint Hypermobility in Adolescent Idiopathic Scoliosis: Greater Curve Flexibility, Larger Thoracic Kyphosis, but Higher Complication Risk

Orthopaedic Surgery, EarlyView.
Generalized joint hypermobility in adolescent idiopathic scoliosis is linked to greater spinal flexibility and increased thoracic kyphosis, but also elevates the risk of surgical complications, despite no significant differences in patient‐reported outcomes.
Di Liu, Kexin Xu, Xiangjie Yin, Terry Jianguo Zhang, Nan Wu, on behalf of the Deciphering Disorders Involving Scoliosis and Comorbidities study   +5 more
wiley   +1 more source

Dynamic stabilization for degenerative diseases in the lumbar spine: 2 years results

Orthopedic Reviews, 2018
Following lumbar fusion, adjacent segment degeneration has been frequently reported. Dynamic systems are believed to reduce main fusion drawbacks. We conducted a retrospective study on patients with degenerative lumbar disease treated with posterior ...
Ahmed Hosny Khalifa, Timo Stübig, Oliver Meier, Christian Walter Müller   +3 more
doaj   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1552-1566, June 2026.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Degenerative findings in lumbar spine MRI: an inter-rater reliability study involving three raters

Chiropractic & Manual Therapies, 2020
Background For diagnostic procedures to be clinically useful, they must be reliable. The interpretation of lumbar spine MRI scans is subject to variability and there is a lack of studies where reliability of multiple degenerative pathologies are rated ...
Klaus Doktor, Tue Secher Jensen, Henrik Wulff Christensen, Ulrich Fredberg, Morten Kindt, Eleanor Boyle, Jan Hartvigsen   +6 more
doaj   +1 more source

Limited correction of lumbar lordosis in the treatment of degenerative scoliosis

Medicine, 2020
Abstract Background: Patients suffering from degenerative scoliosis (DS) were commonly associated with coronal and sagittal imbalance which made deformity correction surgery necessary. The study aimed to explore the efficacy and feasibility of the limited correction of lumbar lordosis (LL) in the treatment of patients
Liang, Yan, Tang, Xiangyu, Zhao, Yongfei, Song, Kai, Mao, Keya, Liu, Haiying, Wang, Zheng   +6 more
openaire   +2 more sources

A Novel Decomposition‐Based Growth Model for Simulating Stress‐Modulated Spinal Growth

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 6, June 2026.
This study introduces the first decomposition‐based finite‐strain growth model for a simplified Functional Spinal Unit, where growth occurs simultaneously with mechanical loading. The approach eliminates the major physical inconsistency of sequential methods—growth in an artificial stress‐free configuration—while preventing mesh distortion and ...
Serhat Onur Çakmak, Ercan Gürses
wiley   +1 more source

Analysis on the related factors of misplacement of freehand pedicle screws via posterior approach in degenerative scoliosis

BMC Musculoskeletal Disorders
Background To study the risk factors associated with misplacement of freehand pedicle screws through a posterior approach for degenerative scoliosis.
ChangJin Guo, RuiYang Wang, Neng Ru, Qing Liu, Fan Zhang, Jie Liang, Yu Wu, LeYuan Chen   +7 more
doaj   +1 more source

Surgical treatment for adult spinal deformity: Conceptual approach and surgical strategy

Spine Surgery and Related Research, 2017
Planning of surgical treatment requires determination of whether osteoarthritis of the spine with lumbar pain should be treated as spinal canal stenosis with or without deformity or as lumbar degenerative scoliosis and clarification of whether treatment ...
Yukihiro Matsuyama
doaj   +1 more source

Associations of lumbar scoliosis with presentation of suspected early axial spondyloarthritis

, 2020
Objective: Scoliosis may impact the mechanical loading and cause secondary changes of the sacroiliac joints and lumbar spine. Our goal was to look how lumbar scoliosis modify the clinical and imaging-study in patients with recent-onset inflammatory back ...
Feydy, A., Voirin-Hertz, M., Marhadour, T., Alegria, G.C., Heijde, D. van der, Saraux, A., Simon, A., Reijnierse, M., Claudepierre, P., Garrigues, F., Loeuille, D.   +10 more
core   +1 more source

Genetic Bone Diseases: A Scoping Review of Pathology, Symptoms, Diagnosis, Treatment, and New Horizons

Advanced Genetics, Volume 7, Issue 2, June 2026.
This review highlights six genetic diseases of the bone, aiming to provide clinicians and researchers with updated information on their diagnosis and treatment. It also includes an assessment of common clinical and radiographic findings, along with pathophysiology related to diseases.
Colin Jones, Ambalangodage C. Jayasuriya
wiley   +1 more source