Results 61 to 70 of about 5,353 (175)

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, EarlyView.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Original paper
Protective effect on visual functions of long-term use of trimetazidine in treatment of primary open angle glaucoma and degenerative myopia

Archives of Medical Science, 2007
Introduction: The purpose of the study was to evaluate selected visual parameters in the group of patients undergoing long-term treatment with trimetazidine as an adjuvant therapy for primary open angle glaucoma and degenerative myopia.Material and ...
Michał S. Nowak, Katarzyna Wybór, Roman Goś, Alicja Zeman-Miecznik, Arleta Waszczykowska, Mirosław Pastuszka, Anna Kłysik, Agnieszka Gajdowska   +7 more
doaj  

Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between continuous glucose monitoring (CGM)‐derived glycaemic variability indicators and early microvascular changes of the retina and choroid in nondiabetic individuals. Materials and Methods Community‐based individuals at high risk for type 2 diabetes (T2DM) underwent detailed assessments including oral ...
Yan Jiang, Liping Gu, Yuhang Ma, Yuan Qu, Hancong Wan, Kangjia Lv, Qian Zhu, Hao Zhou, Jian Sun, Fei Lu, Xiaowei Li, Yufei Wang, Jian Zhou, Kun Liu, Yufan Wang, Yinchen Shen   +15 more
wiley   +1 more source

Labor Market Monopsony Power and the Dynamic Gains to Openness Reforms

International Economic Review, EarlyView.
ABSTRACT We embed labor market monopsony into a dynamic heterogeneous‐firm general equilibrium model with exporting, horizontal FDI, and rich firm lifecycle dynamics. Rising marginal costs with monopsony slow and limit incumbent firm growth in response to liberalization, shifting adjustment to the extensive margin.
Priyaranjan Jha, Antonio Rodriguez‐Lopez, Adam Hal Spencer   +2 more
wiley   +1 more source

Degenerative myopia: mechanical theories revisited

Annals of Eye Science, 2018
The article discusses the early abandonment of mechanical theories about eye enlargement in degenerative myopia at the turn of the 20th century. At that time, the number of theories about myopia grew unrestricted, but with scant support from the experimental field.
openaire   +1 more source

The positive correlation between the progressive photoreceptor damage and the increased macular leakage indicating the severity of diabetic retinopathy

Journal of Diabetes Investigation, EarlyView.
The dark area of photoreceptor cells, as measured by adaptive optics laser scanning ophthalmoscopy, shows significant enlargement with the progression of diabetic retinopathy (DR). A similar trend is observed for macular vascular leakage assessed by fundus fluorescein angiography. A positive correlation exists between these two parameters, suggesting a
Qi Fang, Bingjie Qiu, Xinyue Xu, Wei Jia, Ru Wang, Qianfeng Wang, Wei Qiang, Lei Zhang, Jingfa Zhang, Haiyan Wang   +9 more
wiley   +1 more source

Direct and indirect costs associated with declining distance visual acuity: A nationwide longitudinal cost‐of‐illness study with 11‐year follow‐up

Acta Ophthalmologica, Volume 104, Issue 5, Page 559-571, August 2026.
Abstract Purpose To examine the direct and indirect costs associated with declining distance visual acuity (VA). Methods A longitudinal approach was applied to a large, nationally representative sample with extensive data, including VA measured at two time points.
Joonas Taipale, Petri Purola, Janika Nättinen, Saku Väätäinen, Seppo Koskinen, Hannu Uusitalo   +5 more
wiley   +1 more source

Conjunctival ultraviolet autofluorescence as a biomarker of outdoor exposure in myopia: a systematic review and meta-analysis

Scientific Reports
Outdoor exposure is considered the primary modifiable risk factor in preventing the development of myopia. This effect is thought to be attributed to the light-induced synthesis and release of dopamine in the retina.
Natali Gutierrez Rodriguez, Aura Ortega Claici, Jorge A. Ramos-Castaneda, Jorge González-Zamora, Valentina Bilbao-Malavé, Miriam de la Puente, Patricia Fernandez-Robredo, Sandra Johanna Garzón-Parra, Manuel Garza-Leon, Sergio Recalde   +9 more
doaj   +1 more source

Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children

Acta Ophthalmologica, Volume 104, Issue 5, Page e578-e589, August 2026.
Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley   +1 more source

Radial keratotomy in India untoward consequences and complications

Indian Journal of Ophthalmology, 1990
R.K. is a surgery of tomorrow. It is still in the stage of evolution. It should be under-taken only for precise indications. Case evaluation and honest advice to the patient is important. The patient should be explained that the worst can happen.
Dhanda R, Kalevar V
doaj