Results 31 to 40 of about 12,592 (146)

Clinical and Radiological Outcomes after Microscopic Bilateral Decompression via a Unilateral Approach for Degenerative Lumbar Disease: Minimum 5-Year Follow-Up [PDF]

open access: yesAsian Spine Journal, 2017
Study DesignA retrospective study.PurposeTo assess postoperative bone regrowth at surgical sites after lumbar decompression with >5 years of follow-up.
Sho Dohzono   +5 more
doaj   +1 more source

Therapeutic Strategy of Percutaneous Transforaminal Endoscopic Decompression for Stenosis Associated With Adult Degenerative Scoliosis

open access: yesGlobal Spine Journal, 2022
Study Design: A retrospective study. Objective: To investigate the effects of percutaneous transforaminal endoscopic decompression (PTED) for lumbar stenosis associated with adult degenerative scoliosis and to analyze the correlation between preoperative
Lin-Yu Jin MM   +6 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Diagnosis and Treatment of Degenerative Lumbar Scoliosis with Root Pain

open access: yesGlobal Spine Journal, 2014
Introduction Degenerative lumbar scoliosis is a common type in degenerative lumbar disease. In clinic, root pain is very general except back pain. The objective of our research is to explain and summarize which segments frequently occur root pain, what ...
Y. Liang
doaj   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

Clinical Outcomes of Extreme Lateral Interbody Fusion in the Treatment of Adult Degenerative Scoliosis

open access: yesThe Scientific World Journal, 2012
Introduction. The use of extreme lateral interbody fusion (XLIF) and other lateral access surgery is rapidly increasing in popularity. However, limited data is available regarding its use in scoliosis surgery. The objective of this study was to evaluate
Adam M. Caputo   +6 more
doaj   +1 more source

Degenerative characteristics of multifidus at different vertebral levels of scoliosis in patients with degenerative lumbar scoliosis and relationship of these degenerative characteristics with surface electromyography activity

open access: yesBMC Musculoskeletal Disorders, 2022
Background Previous studies have investigated the imaging changes of the paravertebral muscles (PVM) in patients with degenerative lumbar scoliosis (DLS); however, most of these studies focused on the apical vertebra (AV) level or compared with the ...
Hongru Xie   +6 more
doaj   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen   +5 more
wiley   +1 more source

Age-Related Progression of Degenerative Lumbar Kyphoscoliosis: A Retrospective Study

open access: yesSpine Surgery and Related Research, 2020
Introduction: Degenerative lumbar kyphoscoliosis is a serious clinical condition that affects activities of daily living. This study aimed to investigate the age-related progression of nonoperative degenerative lumbar kyphoscoliosis, to clarify its final
Yohei Ishihara   +3 more
doaj   +1 more source

Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy

open access: yesAnnals of Neurology, EarlyView.
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos   +46 more
wiley   +1 more source

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