Results 151 to 160 of about 4,421 (195)
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â–¼Insulin degludec for diabetes mellitus
Drug and Therapeutics Bulletin, 2013Over the last few years there has been a steady increase in the number of prescriptions dispensed in primary care for intermediate and long-acting insulin analogues and a reduction in prescriptions for biphasic isophane insulin. For example, in England, the volume of intermediate and long-acting insulin analogues in general practice has risen from ...
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Expression, purification, and characterization of the Degludec precursor DesB30
Protein Expression and Purification, 2019Diabetes is a chronic metabolic disease, for which recombinant human insulin is the most effective and mainstream treatment. DesB30 is an insulin analogue in which the B chain lacks amino acid 30 (Thr) compared with human insulin. This analogue can be used to produce the long-acting insulin Degludec or Detemir. In this study, a spacer peptide was added
Junyi, Wu +5 more
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Insulin Degludec: A Novel Basal Insulin Analogue
Annals of Pharmacotherapy, 2013OBJECTIVE: To review the pharmacology, pharmacokinetics, clinical trial data, adverse effects, and potential role in therapy of insulin degludec. DATA SOURCES: Articles were identified using the MEDLINE database (January 1996-December ...
Jennifer D, Goldman-Levine +2 more
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