Results 41 to 50 of about 22,703 (264)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Predição do Consumo Voluntário do Capim-Tanzânia (Panicum maximum, J. cv. tanzânia), sob Pastejo, por Vacas em Lactação, a partir das Características de Degradação Prediction of Tanzania Grass (Panicum Maximum, J.) Voluntary Intake, under Grazing by Lactating Cows, from Degradation Characteristics

open access: yesRevista Brasileira de Zootecnia, 2001
O consumo de matéria seca (CMS) do capim tanzânia de 24 vacas lactantes mestiças (HPB x Gir) e Gir, sob pastejo, foi estimado no mês de janeiro de 1998, a partir da relação entre a digestibilidade da MS da forragem e a produção fecal obtida com auxílio ...
João Paulo Guimarães Soares   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Validation of in situ disappearance curves utilizing mathematical models for incubating fish meal and cottonseed meal

open access: yesSemina: Ciências Agrárias, 2020
Four mathematical models were used to describe the ruminal disappearance of dry matter (DM) and crude protein (CP) of fish meal and cottonseed meal. Results of DM degradability particularity showed that all the models fitted well (R2 > 0.95), however ...
Valiollah Palangi, Maghsoud Besharati
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Estudo comparativo da cinética de degradação ruminal de forragens tropicais em bovinos e ovinos Comparative study of ruminal degradation kinetics of tropical forages in cattle and sheep

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Estimaram-se os parâmetros da cinética de degradação ruminal in situ da fibra em detergente neutro (DgFDN) da cana-de-açúcar e das silagens de capim-elefante, de milho e de sorgo em diferentes tempos de incubação, tamanhos de partícula (1 e 2mm) e ...
P.R.S.S. Campos   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cinética ruminal da degradação de nutrientes da silagem de milho em ambiente ruminal inoculado com diferentes aditivos Ruminal degradation kinetics of corn silage in bulls inoculated with different additives in the rumen

open access: yesRevista Brasileira de Zootecnia, 2006
Objetivou-se avaliar a cinética ruminal da degradação de MS, PB e FDN da silagem de milho em ambiente ruminal inoculado com diferentes aditivos. Utilizou-se um delineamento em quadrado latino 4 x 4, com quatro bovinos holandeses e quatro períodos de ...
Pedro Andrade Katsuki   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Degradabilidade ruminal da cama de frango e do feno de capim coast-cross e avaliação de modelos matemáticos para estimativa da taxa de passagem de partículas Coast-cross hay and broiler litter ruminal degradation and evaluation of mathematical models to estimate rate of particulate passage

open access: yesRevista Brasileira de Zootecnia, 1999
O experimento foi realizado para avaliar a cinética de degradação ruminal da matéria seca (MS), proteína bruta (PB) e fibra em detergente neutro (FDN) e os diferentes modelos para estimativa da taxa de passagem, em novilhos recebendo dietas com 15,0% de ...
Ronaldo Lopes Oliveira   +3 more
doaj   +1 more source

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