Results 91 to 100 of about 2,207 (172)

Structure-Based Discovery of Potent and Selective Small-Molecule α5β1 Integrin Inhibitors for Asthma Therapy. [PDF]

ACS Omega
Beresis R, Sundaram A, Jo H, Adler M, Wang Z, McIntosh J, Yeon SK, Huang Q, Ngo G, Sheppard D, DeGrado WF.   +10 more
europepmc   +1 more source

Molecular biophysics and inhibition mechanism of influenza virus A M2 viroporin by adamantane-based drugs - Challenges in designing antiviral agents. [PDF]

J Struct Biol X
Georgiou K, Kolokouris D, Kolocouris A.
europepmc   +1 more source

Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes. [PDF]

Sci Adv
Grau B, Kormos R, Bañó-Polo M, Chen K, García-Murria MJ, Hajredini F, Sánchez Del Pino MM, Jo H, Martínez-Gil L, von Heijne G, DeGrado WF, Mingarro I.   +11 more
europepmc   +1 more source

SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex. [PDF]

J Am Chem Soc
Schnaider L, Tan S, Singh PR, Capuano F, Scott AJ, Hambley R, Lu L, Yang H, Wallace EJ, Jo H, DeGrado WF.   +10 more
europepmc   +1 more source

Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats. [PDF]

Proc Natl Acad Sci U S A
Celona B, Salomonsson SE, Wu H, Dang B, Kratochvil HT, Clelland CD, DeGrado WF, Black BL.   +7 more
europepmc   +1 more source

Porphyrins as cofactors in enzyme-catalyzed organic reactions. [PDF]

Biophys Rep
Wang R, Zhang J.
europepmc   +1 more source

Breaking symmetry: Metal-guided assembly of heterotrimeric coiled coils. [PDF]

Methods Enzymol
La Gatta S, Pecoraro VL.
europepmc   +1 more source

De novo design of drug-binding proteins with predictable binding energy and specificity. [PDF]

Science
Lu L, Gou X, Tan SK, Mann SI, Yang H, Zhong X, Gazgalis D, Valdiviezo J, Jo H, Wu Y, Diolaiti ME, Ashworth A, Polizzi NF, DeGrado WF.   +13 more
europepmc   +1 more source

Evaluating the incidence of acute kidney injury and gentamicin synergy dosing for endocarditis. [PDF]

JAC Antimicrob Resist
Starkel S, Goodberlet M, Schuler B, Rock A, DeGrado JR, Pearson JC.   +5 more
europepmc   +1 more source

Docking for Molecules That Bind in a Symmetric Stack with SymDOCK. [PDF]

J Chem Inf Model
Smith MS, Knight IS, Kormos RC, Pepe JG, Kunach P, Diamond MI, Shahmoradian SH, Irwin JJ, DeGrado WF, Shoichet BK.   +9 more
europepmc   +1 more source