Results 71 to 80 of about 2,207 (172)

De novo design of porphyrin-containing proteins as efficient and stereoselective catalysts. [PDF]

Science
Hou K, Huang W, Qi M, Tugwell TH, Alturaifi TM, Chen Y, Zhang X, Lu L, Mann SI, Liu P, Yang Y, DeGrado WF.   +11 more
europepmc   +1 more source

Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads. [PDF]

ACS Omega
Stanley-Smith AE, Coates N, Fox JC, Delfino F, Degrado S, Kunz A, Mao S, Zhao F, Garforth B, Hold A, Hong H, Kendall J, Lane J, Meï C, Murphy A, Pogwizd J, Escobar CR, Wertz B, Moss SJ, Gregory MA, Nittoli T.   +20 more
europepmc   +1 more source

EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. [PDF]

Proc Natl Acad Sci U S A, 2023
Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C.   +9 more
europepmc   +1 more source

De novo design of four-helix bundle proteins to bind metalloporphyrin cofactors. [PDF]

Methods Enzymol
Coronado KR, Zhu Y, Mann SI.
europepmc   +1 more source

Peptide bonds strike back. [PDF]

IUCrJ
Chari A.
europepmc   +1 more source

Hexamethylene amiloride binds the SARS-CoV-2 envelope protein at the protein-lipid interface. [PDF]

Protein Sci, 2023
Somberg NH, Medeiros-Silva J, Jo H, Wang J, DeGrado WF, Hong M.   +5 more
europepmc   +1 more source

A Designed Zn²⁺ Sensor Domain Transmits Binding Information to Transmembrane Histidine Kinases. [PDF]

J Am Chem Soc
Hatstat AK, Kormos R, Xu V, Du G, Liu L, Zhang SQ, DeGrado WF.   +6 more
europepmc   +1 more source

Corrigendum: Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population. [PDF]

Front Mol Neurosci, 2022
Mehta SQ, Behl S, Day PL, Delgado AM, Larson NB, Stromback LR, Huebner AR, DeGrado TR, Davis JM, Jannetto PJ, Howie F, Pandey MK.   +11 more
europepmc   +1 more source

Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation. [PDF]

Sci Transl Med
Sharma S, Prathigudupu V, Cable C, Serrano LR, Nerella S, Chen A, Hassan G, Lakins J, Valenzuela CL, Tsukui T, Ramamoorthi R, Kim JJ, Willenbring H, Mattis AN, Volk RF, Zaro BW, Coon JJ, Beresis R, DeGrado WF, Weaver VM, Christenson SA, Jo H, Chen JY.   +22 more
europepmc   +1 more source

ProBASS-a language model with sequence and structural features for predicting the effect of mutations on binding affinity. [PDF]

Bioinformatics
Gurusinghe SNS, Wu Y, DeGrado W, Shifman JM.   +3 more
europepmc   +1 more source