Results 11 to 20 of about 2,209 (171)

Impact of software tools and kinetic model selection on myocardial blood flow and flow reserve quantitation in ¹³N-ammonia PET. [PDF]

J Appl Clin Med Phys
Abstract Background Quantitative assessment of myocardial perfusion using 13N‐ammonia PET with compartmental modeling enables evaluation of myocardial flow reserve (MFR) and prediction of patient prognosis. However, the reliability of these assessments can depend on the analytical methods used for quantitation.
Akiya N, Miwa K, Ando A, Miyaji N, Yamao T, Wachi K, Masubuchi M, Kimura S, Ito R, Komatsu A, Horikawa T, Fukushima K, Okizaki A, Miura S.   +13 more
europepmc   +2 more sources

A De Novo Designed Metalloprotein Displays Variable Thermal Stability and Binding Stoichiometry with Transition Metal Ions. [PDF]

Chembiochem
A de novo designed single‐chain coiled coil protein is unfolded in apo‐state but folds up upon addition of divalent transition metal ions Co(II), Ni(II), Cu(II), and Zn(II). The resulting metal‐bound complexes exhibit distinct thermal stability and metal stoichiometry, making this protein a promising starting point for the design of fully metal ...
Rooijakkers B, Verhagen G, Cramer-Blok A, Zuidinga E, Boyle AL.   +4 more
europepmc   +2 more sources

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

Small, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu, Kyeonghyun Kim, Eun Sung Kang, Hayeon Bae, Seungmin Ryu, Suhyeon Kim, Yeontae Jang, Bok‐Soo Lee, Jiyoung Nam, Minah Suh, Jaecheol Lee, Seung‐gu Kang, Jaekyung Hyun, Huong T. Kratochvil, Yong Ho Kim   +16 more
wiley   +1 more source

From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
Simple catalytic systems that may have operated under prebiotic conditions offer useful molecular principles for the design of modern functional materials. By examining how amino acids, peptide assemblies, and metal complexes achieve catalysis through simple chemical features, this review highlights how prebiotic chemistry can inspire new strategies ...
Omer Agazani, Meital Reches
wiley   +1 more source

Guidare all’integrazione di testo e figure durante lo studio dei multimedia

Formare, 2015
Lo scopo di questo saggio è esaminare alcune delle problematiche che accompagnano l’elaborazione del testo con figure, in particolare quelle legate a comportamenti di economia cognitiva che portano ad elaborare solo parte del materiale.
Gisella Paoletti
doaj   +1 more source

De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects

MedComm, Volume 7, Issue 7, July 2026.
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley   +1 more source

Una resistenza “verde” contro il degrado urbano: il Guerrilla Gardening

Ri-vista: Ricerche per la Progettazione del Paesaggio, 2015
In the early 1970’s, a small group of American ambientalists squatted a vacant lot in Manhattan to create a small garden in response to the scarcity of public space in their neighbourhood.
Francesco Berni
doaj   +1 more source

CRISPR/Cas9‐based white pupae mutant lines in Bactrocera spp. for sterile insect technique applications

Insect Science, Volume 33, Issue 2, Page 463-475, April 2026.
Bactrocera fruit flies are significant horticultural pests that cause major economic losses. A “neoclassical approach” incorporating genome editing via CRISPR/Cas9 to develop genetic sexing strains (GSS) could render the sterile insect technique (SIT) against these pests more efficient and cost‐effective.
Chrysanthi Ioannidou, Maria‐Eleni Gregoriou, Marc F. Schetelig, Elena Drosopoulou, Kostas D. Mathiopoulos, Kostas Bourtzis   +5 more
wiley   +1 more source

Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems

Angewandte Chemie, Volume 137, Issue 34, August 18, 2025.
The inherent chirality, tunability, biocompatibility, and robustness of peptides provide an exciting opportunity for supramolecular chemistry. In this mini‐review, we explore uses of peptides in discrete supramolecular systems, how chemists can draw inspiration from larger biological assemblies, and discuss how embracing the complexity of peptide ...
Ben E. Barber, Ellen M. G. Jamieson, Leah E. M. White, Charlie T. McTernan   +3 more
wiley   +2 more sources

Caratteri, materiali, degrado

, 2023
Catalogo della mostra dei lavori degli studenti dell’Università Iuav di Venezia. L’interessante e rara occasione di studio, è stata resa possibile da Vela Spa, incaricata della gestione per conto del Comune delle maestose Galeazze dell’Arsenale di Venezia.
Trovo', Francesco, Fiorentino, Giuseppe
openaire   +1 more source