Results 21 to 30 of about 2,209 (171)
Compounds 1j, 1l, 2b, 2j, 3g, and 3l were found to have potent anti‐Alzheimer agents for AChE, BChE inhibitions, neuroprotective effects in the presence of H2O2 and GSK3β inhibitions. ABSTRACT A series of benzimidazoles and its analogs (benzoxazoles and benzothiazoles) bearing a benzohydrazide‐hydrazones moiety at the 2‐position were designed and ...
Gözde Sayar +5 more
wiley +1 more source
Chemical Methods for Peptide and Protein Backbone Cleavage
Protein cleavage plays essential roles in biology and is powerful for protein manipulation and functionalization as well as in recombinant expression and purification. Here, the historical background and most recent examples of chemical methods for protein and peptide backbone cleavage are discussed (part of the figure was generated in BioRender).
Miguel Angel Alena‐Rodriguez +1 more
wiley +1 more source
Ripresa, resilienza e pedagogia in contrasto alle povertà: Il caso emblematico del progetto VIVRE
Ci troviamo in un mondo caratterizzato da complessità, rapidi cambiamenti e incertezza. In Italia, tutto questo è stato amplificato da una crisi pandemica che si è abbattuta su un Paese già fragile dal punto di vista economico, sociale ed ambientale ...
Caterina Braga
doaj +1 more source
Abstract De novo protein design has enabled the creation of proteins with diverse functionalities that are not found in nature. Despite recent advances, experimental success rates remain inconsistent and context‐dependent, posing a bottleneck for broader applications of de novo design.
Mario Garcia +2 more
wiley +1 more source
Nella Gestione dei servizi da parte della Pubblica Amministrazione riveste una particolare importanza quello dell'illuminazione pubblica generalmente collegato alle forniture dell'energia elettrica.
Redazione Redazione
doaj +2 more sources
Scheduled preservation is an innovative procedure. It is a complex strategy, that combines large-scale risk mitigation with careful organisation of daily activities. Implementing it means creating a new scenario.
Cesare Crova, Francesco Miraglia
doaj +1 more source
The soluble state of the HIV‐1 Vpu protein forms a complex with Ca2+‐calmodulin
Abstract The HIV‐1 Vpu membrane protein is crucial to the virus lifecycle. Our recent studies revealed soluble Vpu oligomers, prompting further investigation into their interactions with cellular proteins. Notably, Vpu may form a complex with calmodulin (CaM) due to its putative CaM‐binding motif; however, experimental proof of this association is ...
Olamide Ishola +6 more
wiley +1 more source
Il Parco Monumentale delle Cascine, a Firenze, ha spesso, nel passato, rappresentato un punto di criticità urbanistica e sociale della città, sia per le difficoltà oggettive di mantenimento e sorveglianza dei 160 ettari, sia per il degrado che ...
Paolo Di Nardo
doaj
Prevention and Maintenance in Archeological Sites
È piuttosto evidente che le strutture archeologiche sono soggette a significative condizioni di rischio per ragioni connesse alla loro vulnerabilità e alla pericolosità ambientale, essendo in genere costituite da strutture ruderizzate, spesso in avanzato
Paolo Gasparoli
doaj +1 more source
The Interplay of Multivalence and Amphiphilicity in Antimicrobial Bottle Brush Copolymers
Antimicrobial polymers based on tert‐butyl acrylamide and aminoethyl acrylamide are varied in composition and architecture (bottle brush vs. linear copolymers). Linear copolymers show drastically increased selectivities, which is likely a result of differing self‐assembly behavior, as bottle brushes form strong intramolecular associations limiting ...
Anne‐Catherine Lehnen +10 more
wiley +1 more source

